Evidence map›Paper›PMID 28876170›Full record

ArticleLGBT health2017

Transgender Women Living with HIV Frequently Take Antiretroviral Therapy and/or Feminizing Hormone Therapy Differently Than Prescribed Due to Drug-Drug Interaction Concerns.

Hannan M Braun, Jury Candelario, Courtney L Hanlon, Eddy R Segura, Jesse L Clark, Judith S Currier, Jordan E Lake

Abstract read
In one paragraph

Article in LGBT health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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  12. Determinants of antiretroviral therapy adherence among transgender women in South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hannan M Braun1 School of Medicine, University of California , San Francisco, San Francisco, California.
Jury Candelario3 APAIT, Special Service for Groups , Los Angeles, California.
Courtney L Hanlon4 Geisel School of Medicine, Dartmouth College , Hanover, New Hampshire.
Eddy R Segura2 South American Program in HIV Prevention Research, Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine , Los Angeles, California.
Jesse L Clark2 South American Program in HIV Prevention Research, Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine , Los Angeles, California.
Judith S Currier2 South American Program in HIV Prevention Research, Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine , Los Angeles, California.
Jordan E Lake2 South American Program in HIV Prevention Research, Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine , Los Angeles, California.
Dartmouth College · USPeruvian University of Applied Sciences · PEUniversity of California, San Francisco · US

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAPHAEL J LANDOVITZ · 1997 to 2026
$53.5M
South American Program in HIV Prevention Research (SAPHIR)R25MH087222 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Karin Nielsen · 2011 to 2026
$3.9M
Inflammation, Fibrosis and End-Organ Disease in HIV-Infected AdultsK23AI110532 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LAKE, JORDAN E · 2014 to 2018
$937k
NIAID NIH HHS K23 AI110532NIMH NIH HHS P30 MH058107NIMH NIH HHS R25 MH087222
6 · The paper itself

Abstract

purposeBoth hormone therapy (HT) and antiretroviral therapy (ART) can be lifesaving for transgender women (TW) living with HIV, but each has side effects and potential drug-drug interactions (DDI). We assessed how concerns about HT-ART interactions affect treatment adherence.

methodsThis study used a cross-sectional survey of TW (n = 87) in Los Angeles, CA.

resultsFifty-four percent were living with HIV; 64% used HT. Only 49% of TW living with HIV discussed ART-HT DDI with their provider; 40% reported not taking ART (12%), HT (12%), or both (16%) as directed due to DDI concerns.

conclusionImperfect HT/ART use and limited provider communication suggests a need for improved HT-ART integration.

Indexed as

Drug InteractionsDrug MonitoringHormone Replacement TherapyTransgender PersonsAnti-HIV AgentsCross-Sectional StudiesFemaleHIV InfectionsHumansLos AngelesMaleMiddle AgedPilot ProjectsAnti-HIV Agentsantiretroviral therapyhealth disparitiesHIVmedication adherencetransgender

Identifiers

PMID28876170
PMCPMC5661861
OpenAlexW2752500446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.