Evidence map›Paper›PMID 28875934›Full record

ArticleeLife2017

ME31B globally represses maternal mRNAs by two distinct mechanisms during the

Miranda Wang, Michael Ly, Andrew Lugowski, John D Laver, Howard D Lipshitz, Craig A Smibert, Olivia S Rissland

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Review
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  8. Article
  9. Review
  10. Muskelin acts as a substrate receptor of the highly regulatedbioRxiv : the preprint server for biology · 2024
    Article
  11. Greatwall-Endos-PP2A/B55Open biology · 2024
    Article
  12. Review
  13. P-body-like condensates in the germline.Seminars in cell & developmental biology · 2024
    Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Cup is essential forRNA biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miranda Wang *Molecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Michael Ly *Molecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
Andrew LugowskiMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
John D LaverDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.
Howard D LipshitzDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.
Craig A SmibertDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.
Olivia S RisslandMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, Canada.ORCID http://orcid.org/0000-0002-2619-6019

Funding

CIHR MOP-14409
6 · The paper itself

Abstract

In animal embryos, control of development is passed from exclusively maternal gene products to those encoded by the embryonic genome in a process referred to as the maternal-to-zygotic transition (MZT). We show that the RNA-binding protein, ME31B, binds to and represses the expression of thousands of maternal mRNAs during the

Indexed as

Down-RegulationGene Expression RegulationAnimalsDEAD-box RNA HelicasesDrosophilaDrosophila ProteinsProtein Serine-Threonine KinasesRibonucleoproteinsRNA, Messenger, Storedcup protein, DrosophilaDEAD-box RNA HelicasesDrosophila ProteinsMe31B protein, Drosophilapng protein, DrosophilaProtein Serine-Threonine KinasesRibonucleoproteinsRNA, Messenger, StoredTRAL protein, Drosophilachromosomesdevelopmental biologyD. melanogastergenesmaternal-to-zygotic transitionME31B/DDX6mRNA decaystem cellstranslation

Identifiers

PMID28875934
PMCPMC5779226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.