ArticleAngewandte Chemie (International ed. in English)2017
Expanding Anti-Stokes Shifting in Triplet-Triplet Annihilation Upconversion for In Vivo Anticancer Prodrug Activation.
Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Meso-electron-withdrawing pentamethine cyanines achieve large anti-Stokes blue-emitting triplet-triplet annihilation upconversion.Nature communications · 2026Article
- Supramolecular Annihilator with DPA Parallelly Arranged by Multiple Hydrogen-Bonding Interactions for Enhanced Triplet-Triplet Annihilation Upconversion.Molecules (Basel, Switzerland) · 2024Article
- Molecular near-infrared triplet-triplet annihilation upconversion with eigen oxygen immunity.Nature communications · 2024Article
- Light-Responsive and Dual-Targeting Liposomes: From Mechanisms to Targeting Strategies.Molecules (Basel, Switzerland) · 2024Review
- Water-Stable Upconverting Coordination Polymer Nanoparticles for Transparent Films and Anticounterfeiting Patterns with Air-Stable Upconversion.ACS applied materials & interfaces · 2023Article
- Blue-to-UVB Upconversion, Solvent Sensitization and Challenging Bond Activation Enabled by a Benzene-Based Annihilator.Angewandte Chemie (International ed. in English) · 2023Article
- Red Light-Responsive Upconverting Nanoparticles for Quantitative and Controlled Release of a Coumarin-Based Prodrug.Advanced healthcare materials · 2023Article
- Importance of Rose Bengal Loaded with Nanoparticles for Anti-Cancer Photodynamic Therapy.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Upconversion Nanostructures Applied in Theranostic Systems.International journal of molecular sciences · 2022Review
- Analysis of MnBiosensors · 2022Article
- Organic Polymer Hosts for Triplet-Triplet Annihilation Upconversion Systems.Macromolecules · 2021Review
- Enzymatic enhancing of triplet-triplet annihilation upconversion by breaking oxygen quenching for background-free biological sensing.Nature communications · 2021Article
- 796 nm Activation of a Photocleavable Ruthenium(II) Complex Conjugated to an Upconverting Nanoparticle through Two Phosphonate Groups.Inorganic chemistry · 2020Article
- Near-infrared photoresponsive drug delivery nanosystems for cancer photo-chemotherapy.Journal of nanobiotechnology · 2020Review
- Rational design of an "all-in-one" phototheranostic.Chemical science · 2020Article
- Electronic structure engineering and biomedical applications of low energy-excited persistent luminescence nanoparticles.Nanoscale advances · 2020Review
- Development of a novel anti-tumor theranostic platform: a near-infrared molecular upconversion sensitizer for deep-seated cancer photodynamic therapy.Chemical science · 2019Article
- Anti-Stokes Stress Sensing: Mechanochemical Activation of Triplet-Triplet Annihilation Photon Upconversion.Angewandte Chemie (International ed. in English) · 2019Article
- Preparation and application of solid-state upconversion materials based on sodium polyacrylate.RSC advances · 2019Article
- Designing next generation of photon upconversion: Recent advances in organic triplet-triplet annihilation upconversion nanoparticles.Biomaterials · 2019Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
A strategy to expand anti-Stokes shifting from the far-red to deep-blue region in metal-free triplet-triplet annihilation upconversion (TTA-UC) is presented. The method is demonstrated by in vivo titration of the photorelease of an anticancer prodrug. This new TTA system has robust brightness and the longest anti-Stokes shift of any reported TTA system. TTA core-shell-structured prodrug delivery capsules that benefit from these properties were developed; they can operate with low-power density far-red light-emitting diode light. These capsules contain mesoporous silica nanoparticles preloaded with TTA molecules as the core, and amphiphilic polymers encapsulating anticancer prodrug molecules as the shell. When stimulated by far-red light, the intense TTA upconversion blue emission in the system activates the anticancer prodrug molecules and shows effective tumor growth inhibition in vivo. This work paves the way to new organic TTA upconversion techniques that are applicable to in vivo photocontrollable drug release and other biophotonic applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.