Evidence map›Paper›PMID 28875499›Full record

ArticleEuropean journal of immunology2018

The intestinal microbiota determines the colitis-inducing potential of T-bet-deficient Th cells in mice.

Jakob Zimmermann, Pawel Durek, Anja A Kühl, Florian Schattenberg, Patrick Maschmeyer, Francesco Siracusa, Katrin Lehmann, Kerstin Westendorf, Melanie Weber, René Riedel and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Murine T-Cell Transfer Colitis as a Model for Inflammatory Bowel Disease.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jakob ZimmermannDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.ORCID 0000-0002-6302-6844
Pawel DurekDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.
Anja A KühlCharité Universitätsmedizin, Campus Benjamin Franklin, Berlin, Germany.
Florian SchattenbergHelmholtzzentrum für Umweltforschung (UFZ) Leipzig, Department Umweltmikrobiologie, Leipzig, Germany.
Patrick MaschmeyerDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.
Francesco SiracusaDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.ORCID 0000-0001-6047-7351
Katrin LehmannDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.
Kerstin WestendorfDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.
Melanie WeberDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.
René RiedelDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.
Susann MüllerHelmholtzzentrum für Umweltforschung (UFZ) Leipzig, Department Umweltmikrobiologie, Leipzig, Germany.
Andreas RadbruchDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.ORCID 0000-0001-5753-0000
Hyun-Dong ChangDeutsches Rheumaforschungszentrum Berlin (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conflicting evidence has been provided as to whether induction of intestinal inflammation by adoptive transfer of naïve T cells into Rag

Indexed as

Adoptive TransferAnimalsCell DifferentiationColitisDisease Models, AnimalGastrointestinal MicrobiomeHomeodomain ProteinsInflammationLymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutT-bet Transcription FactorT-Box Domain ProteinsT-Lymphocytes, Helper-InducerT-Lymphocyte SubsetsHomeodomain ProteinsRAG-1 proteinT-bet Transcription FactorT-Box Domain ProteinsInflammatory bowel diseaseMicrobiotaT-betT cell transfer colitisT helper cells

Identifiers

PMID28875499
PMCPMC5813160

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.