Evidence map›Paper›PMID 28875472›Full record

ArticleNanoscale research letters2017

Evaluation of Novel

Pengcheng Hu, Dengfeng Cheng, Tao Huang, Anna B Banizs, Jie Xiao, Guobing Liu, Quan Chen, Yuenan Wang, Jiang He, Hongcheng Shi

Open access · goldAbstract read
In one paragraph

Article in Nanoscale research letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Diffusion-weighted MRI andEuropean journal of nuclear medicine and molecular imaging · 2019
    Article
  6. Article
  7. AGuIXThe British journal of radiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Pengcheng HuDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Dengfeng ChengDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Tao HuangDepartment of Radiology and Medical Imaging, University of Virginia, 480 Ray C Hunt Dr., PO Box 801339, Charlottesville, VA, 22903, USA.
Anna B BanizsDepartment of Radiology and Medical Imaging, University of Virginia, 480 Ray C Hunt Dr., PO Box 801339, Charlottesville, VA, 22903, USA.
Jie XiaoDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Guobing LiuDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Quan ChenDepartment of Radiation Oncology, University of Virginia, Charlottesville, VA, 22903, USA.
Yuenan WangDepartment of Radiation Oncology, University of Virginia, Charlottesville, VA, 22903, USA.
Jiang HeDepartment of Radiology and Medical Imaging, University of Virginia, 480 Ray C Hunt Dr., PO Box 801339, Charlottesville, VA, 22903, USA. hejiang216@gmail.com.ORCID http://orcid.org/0000-0001-7600-4604
Hongcheng ShiDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. shihongcheng163@163.com.
Sun Yat-sen University · CNUniversity of Virginia · USFudan University · CNUniversity of Virginia Medical Center · US

Funding

Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Thomas P. Loughran · 1987 to 2026
$72.1M
Novel systemic delivery of siRNA for atherosclerosisR21HL120003 · NHLBI · UNIVERSITY OF VIRGINIA · PI HE, JIANG · 2014 to 2015
$431k
NCI NIH HHS P30 CA044579NHLBI NIH HHS R21 HL120003
6 · The paper itself

Abstract

Radiation therapy of liver cancer is limited by low tolerance of the liver to radiation. Radiosensitizers can effectively reduce the required radiation dose. AGuIX nanoparticles are small, multifunctional gadolinium-based nanoparticles that can carry radioisotopes or fluorescent markers for single-photon emission computed tomography (SPECT), positron emission tomography (PET), fluorescence imaging, and even multimodality imaging. In addition, due to the high atomic number of gadolinium, it can also serve as a tumor radiation sensitizer. It is critical to define the biodistribution and pharmacokinetics of these gadolinium-based nanoparticles to quantitate the magnitude and duration of their retention within the tumor microenvironment during radiotherapy. Therefore, in this study, we successfully labeled AGuIX with

Indexed as

CancerMolecular imagingMRINanoparticlesPETRadiotherapy

Identifiers

PMID28875472
PMCPMC5585112
OpenAlexW2753402478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.