ArticleNeuroradiology2017
Is there an association between flow diverter fish mouthing and delayed-type hypersensitivity to metals?-a case-control study.
Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Incidence of Fish-mouthing and Wall Malapposition of Different Flow Diverters in the Treatment of Cerebral Aneurysms: Device-specific Findings in a Retrospective Single-center Analysis.Clinical neuroradiology · 2026Article
- Twelve-Month Outcomes of the J-Tube Flow-Diverting Stent for Unruptured Intracranial Aneurysms: a Prospective Multicenter Study.Clinical neuroradiology · 2026Article
- Incidence and Outcomes of Flow Diverter Braid Deformation following Treatment with Non-DFT Wire Devices.Neurologia medico-chirurgica · 2026Article
- Postoperative acute ultra-early fish mouthing of a Surpass Evolve flow diverter leading to ischemic complication.Radiology case reports · 2026Article
- A novel approach to nickel allergy in neurointerventional surgery: Peripheral arterial stent testing protocol to guide the choice of cerebral aneurysm treatment.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Endovascular Management of Unruptured Cerebral Aneurysms in Patients with Nickel Allergy: Three Cases.Journal of neuroendovascular therapy · 2025Article
- Ultra-Early "Fishmouth stenosis" and thrombosis of a Surpass Evolve flow diversion device following treatment of multiples right siphon aneurysms.Neuroradiology · 2023Article
- Pipeline Flex embolisation device with Shield Technology for the treatment of patients with intracranial aneurysms: periprocedural and 6 month outcomes.The neuroradiology journal · 2020Article
- Two- to five-year follow-up of 78 patients after treatment with the Flow Redirection Endoluminal Device.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020Article
- Delayed Stroke after Aneurysm Treatment with Flow Diverters in Small Cerebral Vessels: A Potentially Critical Complication Caused by Subacute Vasospasm.Journal of clinical medicine · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFlow diverters are increasingly used in the treatment of complex and giant intracranial aneurysms. However, they are associated with complications like late aneurysmal rupture. Additionally, flow diverters show focal structural decrease in luminal diameter without any intimal hyperplasia. This resembles a "fish mouth" when viewed en face. In this pilot study, we tested the hypothesis of a possible association between flow diverter fish-mouthing and delayed-type hypersensitivity to its metal constituents.
methodsWe retrospectively reviewed patient records from our center between May 2010 and November 2015. A total of nine patients had flow diverter fish mouthing. A control group of 25 patients was selected. All study participants underwent prospective patch test to detect hypersensitivity to flow diverter metal constituents. Analysis was performed using logistic regression analysis and Wilcoxon sign rank sum test. Univariate and multivariate analyses were performed to test variables to predict flow diverter fish mouthing.
resultsThe association between flow diverter fish mouthing and positive patch test was not statistically significant. In multivariate analysis, history of allergy and maximum aneurysm size category was associated with flow diverter fish mouthing. This was further confirmed on Wilcoxon sign rank sum test.
conclusionThe study showed statistically significant association between flow diverter fish mouthing and history of contact allergy and a small aneurysmal size. Further large-scale studies are needed to detect a statistically significant association between flow diverter fish mouthing and patch test. We recommend early and more frequent follow-up imaging in patients with contact allergy to detect flow diverter fish mouthing and its subsequent evolution.
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