Evidence map›Paper›PMID 28875060›Full record

ArticleJournal of caffeine research2017

Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans.

Hui He, Dejian Ma, Laura Brooks Crone, Matthew Butawan, Bernd Meibohm, Richard J Bloomer, Charles R Yates

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of caffeine research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05170113 (A Pilot, Randomized, Double-blind, Placebo-controlled, Parallel Design Study to Evaluate the Effectiveness and Safety of an Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health Among Overall Healthy Participants), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05170113 nacompletednot on this mapstarted 2021, after this paper: background citation

A Pilot, Randomized, Double-blind, Placebo-controlled, Parallel Design Study to Evaluate the Effectiveness and Safety of an Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health Among Overall Healthy Participants

TypeinterventionalSponsorSupplement Formulators, Inc.Ran2021 to 2022Enrolled79ConditionsFatigueArmsAlpinia galanga formulation, Theacrine formulation, Caffeine formulation, Placebo
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Theacrine as a novel ergogenic aid: impact on canoe sprint performance.Journal of the International Society of Sports Nutrition · 2025
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  11. Theacrine FromFrontiers in nutrition · 2020
    Review
  12. Directly compressed rosuvastatin calcium tablets that offer hydrotropic and micellar solubilization for improved dissolution rate and extent of drug release.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hui HeDepartment of Pharmaceutical Sciences, University of Tennessee College of Pharmacy, Memphis, Tennessee.
Dejian MaDepartment of Pharmaceutical Sciences, University of Tennessee College of Pharmacy, Memphis, Tennessee.
Laura Brooks CroneCardiorespiratory/Metabolic Laboratory, School of Health Studies, University of Memphis, Memphis, Tennessee.
Matthew ButawanCardiorespiratory/Metabolic Laboratory, School of Health Studies, University of Memphis, Memphis, Tennessee.
Bernd MeibohmDepartment of Pharmaceutical Sciences, University of Tennessee College of Pharmacy, Memphis, Tennessee.
Richard J BloomerCardiorespiratory/Metabolic Laboratory, School of Health Studies, University of Memphis, Memphis, Tennessee.
Charles R YatesDepartment of Pharmaceutical Sciences, University of Tennessee College of Pharmacy, Memphis, Tennessee.
University of Tennessee Health Science Center · US

Funding

Mass Spectrometer for Small Molecule Drug DevelopmentS10OD016226 · OD · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI MEIBOHM, BERND · 2014 to 2014
$316k
NIH HHS S10 OD016226
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

caffeinepharmacokineticstheacrine

Identifiers

PMID28875060
PMCPMC5582588
OpenAlexW2735086467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.