Evidence map›Paper›PMID 28874767›Full record

ArticleScientific reports2017

A cross-sectional comparative study of gut bacterial community of Indian and Finnish children.

Shreyas V Kumbhare, Himanshu Kumar, Somak P Chowdhury, Dhiraj P Dhotre, Akihito Endo, Jaana Mättö, Arthur C Ouwehand, Samuli Rautava, Ruchi Joshi, Nitinkumar P Patil and 5 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Microbial Journey: Mount Everest to Mars.Indian journal of microbiology · 2022
    Review
  7. Article
  8. Observational
  9. Article
  10. TheFrontiers in cellular and infection microbiology · 2021
    Article
  11. Can the FUT2Frontiers in nutrition · 2020
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shreyas V KumbhareDepartment of Microbiology, R.C. Patel Arts, Science, and Commerce College, Shirpur, Dist. Dhule, Maharashtra, 425405, India.
Himanshu KumarFunctional Foods Forum, Faculty of medicine, University of Turku, Turku, 20520, Finland.
Somak P ChowdhuryNational Centre for Cell Science, Savitribai Phule University of Pune campus, Ganeshkhind, Pune, Maharashtra, 411007, India.
Dhiraj P DhotreNational Centre for Cell Science, Savitribai Phule University of Pune campus, Ganeshkhind, Pune, Maharashtra, 411007, India.
Akihito EndoDepartment of Food and Cosmetic Science, Tokyo University of Agriculture, Hokkaido, Japan.
Jaana MättöFinnish Red Cross Blood Service, Kivihaantie 7, Helsinki, 00310, Finland.
Arthur C OuwehandActive Nutrition, DuPont Nutrition & Health, Kantvik, 02460, Finland.
Samuli RautavaFunctional Foods Forum, Faculty of medicine, University of Turku, Turku, 20520, Finland.
Ruchi JoshiKing Edward Memorial hospital research centre, Pune, Maharashtra, 411011, India.
Nitinkumar P PatilDepartment of Microbiology, Smt. Chandibai Himathmal Mansukhani College, Ulhasnagar, Thane, Maharashtra, 421003, India.
Ravindra H PatilDepartment of Microbiology, R.C. Patel Arts, Science, and Commerce College, Shirpur, Dist. Dhule, Maharashtra, 425405, India.
Erika IsolauriDepartment of Paediatrics, University of Turku, Turku, 20520, Finland.
Ashish R BavdekarKing Edward Memorial hospital research centre, Pune, Maharashtra, 411011, India.
Seppo SalminenFunctional Foods Forum, Faculty of medicine, University of Turku, Turku, 20520, Finland. sepsal@utu.fi.
Yogesh S ShoucheNational Centre for Cell Science, Savitribai Phule University of Pune campus, Ganeshkhind, Pune, Maharashtra, 411007, India. yogesh@nccs.res.in.ORCID 0000-0002-5055-5931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut microbiome plays a crucial role in the compositional development of gut microbiota. Though well documented in western pediatrics population, little is known about how various host conditions affect populations in different geographic locations such as the Indian subcontinent. Given the impact of distinct environmental conditions, our study assess the gut bacterial diversity of a small cohort of Indian and Finnish children and investigated the influence of FUT2 secretor status and birth mode on the gut microbiome of these populations. Using multiple profiling techniques, we show that the gut bacterial community structure in 13-14-year-old Indian (n = 47) and Finnish (n = 52) children differs significantly. Specifically, Finnish children possessed higher Blautia and Bifidobacterium, while genera Prevotella and Megasphaera were predominant in Indian children. Our study also demonstrates a strong influence of FUT2 and birth mode variants on specific gut bacterial taxa, influence of which was noticed to differ between the two populations under study.

Indexed as

Gastrointestinal MicrobiomeAdolescentBifidobacteriumFemaleFinlandFucosyltransferasesGalactoside 2-alpha-L-fucosyltransferaseHumansIndiaMaleMegasphaeraPolymorphism, GeneticPrevotellaFucosyltransferasesGalactoside 2-alpha-L-fucosyltransferase

Identifiers

PMID28874767
PMCPMC5585376

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.