ArticleScientific reports2017
Genome Analysis of Staphylococcus capitis TE8 Reveals Repertoire of Antimicrobial Peptides and Adaptation Strategies for Growth on Human Skin.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 39 citations in OpenAlex.
- Staphylococcus capitis strain producing dual bacteriocins, capidermicin and micrococcin P1, shows broad-spectrum antimicrobial activity.Scientific reports · 2026Article
- Review
- Phenotypic Variation inAntibiotics (Basel, Switzerland) · 2024Review
- A Staphylococcus capitis strain with unusual bacteriocin production.Microbial biotechnology · 2023Article
- Dermatological Implications of the Taqiyah and Imamah: Recommendations for Delivering Culturally Conscious Care.Cureus · 2023Article
- Scalp microbiome of healthy women wearing hijab compared to those not wearing hijab: a cross-sectional study.Scientific reports · 2023Article
- Comprehensive Approaches for the Search and Characterization of Staphylococcins.Microorganisms · 2023Article
- Complete Genome Sequence of Staphylococcus capitis CCSM0123, Isolated from Healthy Facial Skin.Microbiology resource announcements · 2023Article
- Review
- The dynamic balance of the skin microbiome across the lifespan.Biochemical Society transactions · 2023Review
- The hemostatic profile of cold-stored whole blood from non-greyhound and greyhound dogs over 42 days.Frontiers in veterinary science · 2023Article
- The fluorescent protein iLOV as a reporter for screening of high-yield production of antimicrobial peptides in Pichia pastoris.Microbial biotechnology · 2022Article
- Phenol-soluble modulins PSMα3 and PSMβ2 form nanotubes that are cross-α amyloids.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Comparative genomics ofFrontiers in microbiology · 2022Article
- Bacteriocin-Like Inhibitory Substances in Staphylococci of Different Origins and Species With Activity Against Relevant Pathogens.Frontiers in microbiology · 2022Article
- The microbiome-shaping roles of bacteriocins.Nature reviews. Microbiology · 2021Review
- Antimicrobials from a feline commensal bacterium inhibit skin infection by drug-resistanteLife · 2021Article
- Identification of a Human Skin Commensal Bacterium that Selectively Kills Cutibacterium acnes.The Journal of investigative dermatology · 2020Article
- Staphylococcal-Produced Bacteriocins and Antimicrobial Peptides: Their Potential as Alternative Treatments forAntibiotics (Basel, Switzerland) · 2020Review
- Nisin J, a Novel Natural Nisin Variant, Is Produced by Staphylococcus capitis Sourced from the Human Skin Microbiota.Journal of bacteriology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Staphylococcus capitis TE8 was isolated from skin surface of a healthy human foot, and exhibited a strong antibacterial activity against Gram-positive bacteria, including Staphylococcus aureus. Whole genome sequence of S. capitis TE8 was obtained by shotgun and paired-end pyrosequencing with a coverage of 109-fold. The draft genome contains 2,516,639 bp in 8 scaffolds with 209 total contigs. The genome contains 2319 protein coding sequences, 58 tRNA and 3 rRNA. Genome sequence analysis revealed 4 distinct gene loci with the ability to encode antimicrobial peptides: (i) an epidermicin gene cluster; (ii) a gallidermin gene cluster; (iii) a gene cluster encoding six phenol soluble modulin (PSM) β-type peptides (PSMβ1-β6) and (iv) an additional gene that belonged to PSMβ family and encoded a 44 residues long peptide, HTP2388. Synthetic peptides with sequence identical to seven PSMβ-like peptides i.e. PSMβ1-β6 and peptide HTP2388 showed antibacterial activity. Genome sequence also revealed genes for adhesins, intracellular adhesins, osmoadaptation, oxidative and acid stress tolerance possibly responsible for initial attachment, colonization and survival of S. capitis TE8 on human skin. Comparative genome analysis revealed presence of a gamut of genes in S. capitis strains in comparison to Staphylococcus epidermidis and Staphylococcus caprae indicating towards their possible role in better adaptation and survival on human skin.
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