Evidence map›Paper›PMID 28874579›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Nitric oxide blocks the development of the human parasite

Jia Shen, De-Hua Lai, R Alan Wilson, Yun-Fu Chen, Li-Fu Wang, Zi-Long Yu, Mei-Yu Li, Ping He, Geoff Hide, Xi Sun and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 51 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Article
  2. Article
  3. Review
  4. Journal of parasitology research · 2024
    Article
  5. Bsep/Abcb11 knockout ameliorates Schistosoma mansoni liver pathology by reducing parasite fecundity.Liver international : official journal of the International Association for the Study of the Liver · 2023
    Article
  6. Article
  7. Review
  8. Host genetic backgrounds: the key to determining parasite-host adaptation.Frontiers in cellular and infection microbiology · 2023
    Review
  9. Review
  10. Article
  11. Nitric oxide in parasitic infections: a friend or foe?Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Review
  12. Article
  13. Article
  14. Recent Advances in the Production of Genome-Edited Rats.International journal of molecular sciences · 2022
    Review
  15. Review
  16. High resistance toiScience · 2021
    Article
  17. Article
  18. Innate Resistance toFrontiers in microbiology · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Jia ShenCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China.
De-Hua LaiCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China.ORCID 0000-0002-4709-1507
R Alan WilsonCentre for Immunology and Infection, Department of Biology, University of York, Heslington, York YO10 5DD, United Kingdom.
Yun-Fu ChenCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China.
Li-Fu WangDepartment of Parasitology, Key Laboratory of Tropical Disease Control of the Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, People's Republic of China.
Zi-Long YuDepartment of Parasitology, Key Laboratory of Tropical Disease Control of the Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, People's Republic of China.
Mei-Yu LiDepartment of Parasitology, Key Laboratory of Tropical Disease Control of the Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, People's Republic of China.
Ping HeDepartment of Parasitology, Key Laboratory of Tropical Disease Control of the Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, People's Republic of China.
Geoff HideBiomedical Research Centre, School of Environment and Life Sciences, University of Salford, Salford M5 4WT, United Kingdom.
Xi SunDepartment of Parasitology, Key Laboratory of Tropical Disease Control of the Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, People's Republic of China.
Ting-Bao YangCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China.
Zhong-Dao WuDepartment of Parasitology, Key Laboratory of Tropical Disease Control of the Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, People's Republic of China; fjayala@uci.edu wuzhd@mail.sysu.edu.cn lsslzr@mail.sysu.edu.cn.
Francisco J AyalaDepartment of Ecology and Evolutionary Biology, Ayala School of Biological Sciences, University of California, Irvine, CA 92697 fjayala@uci.edu wuzhd@mail.sysu.edu.cn lsslzr@mail.sysu.edu.cn.
Zhao-Rong LunCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China; fjayala@uci.edu wuzhd@mail.sysu.edu.cn lsslzr@mail.sysu.edu.cn.
Sun Yat-sen University · CNUniversity of California, Irvine · USUniversity of Salford · GBUniversity of York · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human schistosomiasis, caused by

Indexed as

Host-Parasite InteractionsNitric OxideAdoptive TransferAnimalsCell RespirationFemaleMaleMice, Inbred BALB CNitric Oxide Synthase Type IIRats, Sprague-DawleySchistosoma japonicumNitric OxideNitric Oxide Synthase Type IINos2 protein, ratgranuloma formationmitochondriaratSchistosoma japonicumschistosomiasis

Identifiers

PMID28874579
PMCPMC5617295
OpenAlexW2753418543

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.