Evidence map›Paper›PMID 28874552›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Global transcriptional regulatory network for

Xin Fang, Anand Sastry, Nathan Mih, Donghyuk Kim, Justin Tan, James T Yurkovich, Colton J Lloyd, Ye Gao, Laurence Yang, Bernhard O Palsson

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 117 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The EcoCyc database (2025).EcoSal Plus · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Heliyon · 2024
    Article
  14. Article
  15. Article
  16. The EcoCyc Database (2023).EcoSal Plus · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Xin FangDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093.
Anand SastryDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093.
Nathan MihDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093.
Donghyuk KimDepartment of Genetic Engineering, Kyung Hee University, Yongin 17104, South Korea.
Justin TanDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093.
James T YurkovichDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093.ORCID 0000-0002-9403-509X
Colton J LloydDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093.
Ye GaoDivision of Biological Sciences, University of California at San Diego, La Jolla, CA 92093.
Laurence YangDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093; palsson@ucsd.edu lyang@eng.ucsd.edu.
Bernhard O PalssonDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093; palsson@ucsd.edu lyang@eng.ucsd.edu.
University of California San Diego · USKyung Hee University · KRNovo Nordisk Foundation · DK

Funding

GENOMICALLY BASED MODELS FOR ANTIBIOTIC DEVELOPMENTR01GM057089 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALSSON, BERNHARD O · 1998 to 2021
$6.9M
Multiscale Molecular Systems Biology: Reconstruction and Model OptimizationU01GM102098 · NIGMS · STANFORD UNIVERSITY · PI SAUNDERS, MICHAEL ALAN · 2012 to 2016
$1.8M
NIGMS NIH HHS R01 GM057089NIGMS NIH HHS U01 GM102098
6 · The paper itself

Abstract

Transcriptional regulatory networks (TRNs) have been studied intensely for >25 y. Yet, even for the

Indexed as

Gene Expression Regulation, BacterialGene Regulatory NetworksEscherichia coliTranscription FactorsTranscriptomeTranscription Factorsmatrix factorizationregressiontranscriptional regulationtranscriptomics

Identifiers

PMID28874552
PMCPMC5617254
OpenAlexW2753215236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.