ArticlemBio2017
Pyruvate Accumulation Is the First Line of Cell Defense against Heat Stress in a Fungus.
Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 76 citations in OpenAlex.
- LDH isozymes as targets for cancer therapy.Journal of enzyme inhibition and medicinal chemistry · 2026Review
- Heat stress-induced degradation of glutamine synthetase rebalances central carbon-nitrogen metabolism and promotes thermotolerance inApplied and environmental microbiology · 2026Article
- Glutathione peroxidase gene regulates heat stress response via trehalose synthesis in Pleurotus ostreatus.Applied microbiology and biotechnology · 2026Article
- Insights into the Adaptation ofJournal of fungi (Basel, Switzerland) · 2026Article
- Accumulation of the spontaneous and random mutations is causative of fungal culture degeneration.Fundamental research · 2026Article
- Research progress on heat stress response mechanisms inFrontiers in microbiology · 2026Review
- From the Ground to the Clinic: The Evolution and Adaptation of Fungi.Journal of fungi (Basel, Switzerland) · 2025Review
- Comparative ubiquitinome analysis reveals the roles of protein ubiquitination in the heat stress response fromApplied and environmental microbiology · 2025Article
- Transcriptomic Profiling ofGenes · 2025Article
- Comparative analyses of the biological characteristics, fluconazole resistance, and heat adaptation mechanisms ofApplied and environmental microbiology · 2025Article
- Mr-lac3 and Mr-lcc2 inJournal of fungi (Basel, Switzerland) · 2025Article
- Spermidine enhances the heat tolerance ofApplied and environmental microbiology · 2025Article
- Analysis of the chitin synthase gene family inPeerJ · 2025Article
- Functional Evolution ofJournal of fungi (Basel, Switzerland) · 2024Article
- Article
- Bioinformatics Analysis, Expression Profiling, and Functional Characterization of Heat Shock Proteins inBioengineering (Basel, Switzerland) · 2023Article
- Riboflavin Targets the Cellular Metabolic and Ribosomal Pathways of Candida albicansMicrobiology spectrum · 2023Article
- New Methylcitrate Synthase Inhibitor Induces Proteolysis, Lipid Degradation and Pyruvate Excretion inJournal of fungi (Basel, Switzerland) · 2023Article
- The Production of Pyruvate in Biological Technology: A Critical Review.Microorganisms · 2022Review
- Elevated Level of Cerebrospinal Fluid Pyruvate Dehydrogenase Kinase 4 Is a Predictive Biomarker of Clinical Outcome after Subarachnoid Hemorrhage.Brain sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat tolerance is well known to be key to fungal survival in many habitats, but our mechanistic understanding of how organisms adapt to heat stress is still incomplete. Using
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.