Evidence map›Paper›PMID 28874379›Full record

ArticleAntimicrobial agents and chemotherapy2017

Antagonism between Front-Line Antibiotics Clarithromycin and Amikacin in the Treatment of Mycobacterium abscessus Infections Is Mediated by the

Mark Pryjma, Ján Burian, Kevin Kuchinski, Charles J Thompson

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 65 citations in OpenAlex.

  1. Tobramycin enhancesProceedings of the National Academy of Sciences of the United States of America · 2026
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  2. Establishment of anAntimicrobial agents and chemotherapy · 2026
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  7. Durlobactam in combination with β-lactams to combatAntimicrobial agents and chemotherapy · 2025
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  8. Durlobactam in combination with β-lactams to combatAntimicrobial agents and chemotherapy · 2025
    Article
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  11. Tiny but mighty: Diverse functions of uORFs that regulate gene expression.Computational and structural biotechnology journal · 2024
    Review
  12. Article
  13. Altered serine metabolism promotes drug tolerance inAntimicrobial agents and chemotherapy · 2024
    Article
  14. Altered serine metabolism promotes drug tolerance inAntimicrobial agents and chemotherapy · 2024
    Article
  15. Article
  16. Article
  17. Development of 2nd generation aminomethyl spectinomycins that overcome native efflux inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Exploring antibiotic resistance mechanisms inFrontiers in microbiology · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mark PryjmaDepartment of Microbiology and Immunology and the Centre for Tuberculosis Research, University of British Columbia, Vancouver, Canada.
Ján BurianDepartment of Microbiology and Immunology and the Centre for Tuberculosis Research, University of British Columbia, Vancouver, Canada.
Kevin KuchinskiDepartment of Microbiology and Immunology and the Centre for Tuberculosis Research, University of British Columbia, Vancouver, Canada.
Charles J ThompsonDepartment of Microbiology and Immunology and the Centre for Tuberculosis Research, University of British Columbia, Vancouver, Canada charles.thompson@ubc.ca.
University of British Columbia · CA

Funding

CIHR MOP-82855
6 · The paper itself

Abstract

Combinations of antibiotics, each individually effective against

Indexed as

AmikacinAnti-Bacterial AgentsBacterial ProteinsClarithromycinDrug AntagonismDrug Resistance, Multiple, BacterialGene Expression Regulation, BacterialHumansMicrobial Sensitivity TestsMycobacterium abscessusMycobacterium Infections, NontuberculousAmikacinAnti-Bacterial AgentsBacterial ProteinsClarithromycinamikacinaminoglycosideantagonizeantibiotic resistanceclarithromycincystic fibrosisdrug resistancemacrolideMycobacterium abscessussynergizesynergywhiB7

Identifiers

PMID28874379
PMCPMC5655113
OpenAlexW2752430905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.