Evidence map›Paper›PMID 28874372›Full record

ArticleAntimicrobial agents and chemotherapy2017

Multiple Modes of Action of a Monoclonal Antibody against Multidrug-Resistant Escherichia coli Sequence Type 131-

Luis M Guachalla, Katharina Hartl, Cecília Varga, Lukas Stulik, Irina Mirkina, Stefan Malafa, Eszter Nagy, Gábor Nagy, Valéria Szijártó

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Reprogrammed SimCells for antimicrobial therapy.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. A cynomolgus monkeyInfection and immunity · 2024
    Article
  4. Preclinical validation of anMicrobiology spectrum · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Strategies to Tackle Antimicrobial Resistance: The Example ofInternational journal of molecular sciences · 2021
    Review
  9. Article
  10. Article
  11. Monoclonal antibody-based therapies for bacterial infections.Current opinion in infectious diseases · 2019
    Review
  12. Article
  13. A New Tool for Complement Research:Frontiers in immunology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luis M GuachallaArsanis Biosciences GmbH, Vienna, Austria.
Katharina HartlArsanis Biosciences GmbH, Vienna, Austria.
Cecília VargaArsanis Biosciences GmbH, Vienna, Austria.
Lukas StulikArsanis Biosciences GmbH, Vienna, Austria.
Irina MirkinaArsanis Biosciences GmbH, Vienna, Austria.
Stefan MalafaArsanis Biosciences GmbH, Vienna, Austria.
Eszter NagyArsanis Biosciences GmbH, Vienna, Austria.
Gábor NagyArsanis Biosciences GmbH, Vienna, Austria.
Valéria SzijártóArsanis Biosciences GmbH, Vienna, Austria valeria.szijarto@arsanis.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The multidrug-resistant

Indexed as

AnimalsAnti-Bacterial AgentsAntibodies, MonoclonalBloodCell LineComplement System ProteinsDisease Models, AnimalDrug Resistance, Multiple, BacterialEndotoxemiaEndotoxinsEscherichia coli InfectionsExtraintestinal Pathogenic Escherichia coliFemaleHumansMacrophagesMice, Inbred BALB CAnti-Bacterial AgentsAntibodies, MonoclonalComplement System ProteinsEndotoxinsO Antigenscomplement-mediated killingendotoxin neutralizationEscherichia colimechanism of actionmonoclonal antibodyopsonizationST131

Identifiers

PMID28874372
PMCPMC5655088
OpenAlexW2753777507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.