ArticleJournal of the International Neuropsychological Society : JINS2018
Differences in Neurocognitive Impairment Among HIV-Infected Latinos in the United States.
Article in Journal of the International Neuropsychological Society : JINS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Prevalence and variability of HIV/AIDS-associated neurocognitive impairments in Africa: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- HIV, Vascular Risk Factors, and Cognition in the Combination Antiretroviral Therapy Era: A Systematic Review and Meta-Analysis.Journal of the International Neuropsychological Society : JINS · 2021Pooled it
- Beyond Acculturation: Contextual Factors Predicting Neurocognitive Performance in a Clinical Sample of Latina/o/e Adults.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025Article
- Cerebrospinal fluid biomarkers of inflammation and immune activation associated with neurocognitive impairment among US Latinos with HIV.AIDS (London, England) · 2025Article
- Social Engagement and Neurocognition in Latino and Non-Latino White Older Persons with HIV.AIDS and behavior · 2025Article
- Neurocognitive disparities: investigating ethnicity and mental health in rural aging adults.Aging · 2024Article
- Neurocognition and its predictors in a linguistically and culturally diverse cohort of people with HIV.The Clinical neuropsychologist · 2024Article
- Disparities in Metabolic Syndrome and Neurocognitive Function Among Older Hispanics/Latinos with Human Immunodeficiency Virus.AIDS patient care and STDs · 2024Article
- Emotional health and its association with neurocognition in Hispanic and non-Hispanic White people with HIV.Journal of the International Neuropsychological Society : JINS · 2024Article
- You gotta walk the walk to talk the talk: protocol for a feasibility study of the Happy Older Latino Adults (HOLA) health promotion intervention for older HIV-positive Latino men.Pilot and feasibility studies · 2023Article
- Algorithms for Operationalizing Mild Cognitive Impairment Using the Spanish-Language NIH Toolbox Cognition Battery.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2022Article
- A Multivariate Interpretation of the Spanish-Language NIH Toolbox Cognition Battery: The Normal Frequency of Low Scores.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2022Article
- The neurocognitive effects of a past cannabis use disorder in a diverse sample of people living with HIV.AIDS care · 2021Article
- Utility of a Short Neuropsychological Protocol for Detecting HIV-Associated Neurocognitive Disorders in Patients with Asymptomatic HIV-1 Infection.Brain sciences · 2021Article
- The impact of sociocultural factors on prospective memory performance in HIV+ Latinx adults.Neuropsychology · 2021Article
- Depressive Symptoms Differentially Predict Neurocognition in Latinx and Non-Hispanic White People Living with HIV.Journal of the International Neuropsychological Society : JINS · 2021Article
- Demographically-adjusted norms for selected tests of verbal fluency: Results from the Neuropsychological Norms for the US-Mexico Border Region in Spanish (NP-NUMBRS) project.The Clinical neuropsychologist · 2021Article
- Neurocognitive impairment in Spanish-speaking Latinos living with HIV in the US: Application of the neuropsychological norms for the US-Mexico border region in Spanish (NP-NUMBRS).The Clinical neuropsychologist · 2021Article
- The Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) Project: Overview and considerations for life span research and evidence-based practice.The Clinical neuropsychologist · 2021Article
- Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders.Current topics in behavioral neurosciences · 2021Review
Corrections and comments
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Authors and funding
23 authors at 9 institutions in 1 country.
Funding
Abstract
objectivesHuman immunodeficiency virus (HIV) disproportionately affects Hispanics/Latinos in the United States, yet little is known about neurocognitive impairment (NCI) in this group. We compared the rates of NCI in large well-characterized samples of HIV-infected (HIV+) Latinos and (non-Latino) Whites, and examined HIV-associated NCI among subgroups of Latinos.
methodsParticipants included English-speaking HIV+ adults assessed at six U.S. medical centers (194 Latinos, 600 Whites). For overall group, age: M=42.65 years, SD=8.93; 86% male; education: M=13.17, SD=2.73; 54% had acquired immunodeficiency syndrome. NCI was assessed with a comprehensive test battery with normative corrections for age, education and gender. Covariates examined included HIV-disease characteristics, comorbidities, and genetic ancestry.
resultsCompared with Whites, Latinos had higher rates of global NCI (42% vs. 54%), and domain NCI in executive function, learning, recall, working memory, and processing speed. Latinos also fared worse than Whites on current and historical HIV-disease characteristics, and nadir CD4 partially mediated ethnic differences in NCI. Yet, Latinos continued to have more global NCI [odds ratio (OR)=1.59; 95% confidence interval (CI)=1.13-2.23; p<.01] after adjusting for significant covariates. Higher rates of global NCI were observed with Puerto Rican (n=60; 71%) versus Mexican (n=79, 44%) origin/descent; this disparity persisted in models adjusting for significant covariates (OR=2.40; CI=1.11-5.29; p=.03).
conclusionsHIV+ Latinos, especially of Puerto Rican (vs. Mexican) origin/descent had increased rates of NCI compared with Whites. Differences in rates of NCI were not completely explained by worse HIV-disease characteristics, neurocognitive comorbidities, or genetic ancestry. Future studies should explore culturally relevant psychosocial, biomedical, and genetic factors that might explain these disparities and inform the development of targeted interventions. (JINS, 2018, 24, 163-175).
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