ArticleBMC cancer2017
Prognostic consequences of implementing cancer patient pathways in Denmark: a comparative cohort study of symptomatic cancer patients in primary care.
Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 55 citations in OpenAlex.
- Primary healthcare providers' strategies of handling patients presenting with potential cancer symptoms following the introduction of standardized cancer patient pathways in Sweden.BMC primary care · 2026Article
- Benchmarking Cervical Cancer Care Pathways-Measuring Timelines and Identifying Factors Associated With Delay for Women Undergoing Definitive Radiotherapy in New South Wales, Australia.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- Mapping integrated care for brain tumour-related epilepsy in the Italian RIN-IRCCS network.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Routes to cancer diagnosis for migrants in Denmark: a population-based nationwide cohort study.BMC cancer · 2026Article
- The Association Between Alignment to the Breast Cancer Optimal Care Pathways and Patient Survival in Victoria, Australia, 2012-2019: A Retrospective Population-Based Cohort Study.The Medical journal of Australia · 2026Article
- Comparative analysis of breast cancer care models and patient journeys across six European countries: implications for the Austrian healthcare system.BMC health services research · 2025Article
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- The impact of cancer patient pathway on timing of radiotherapy and survival: a cohort study in glioblastoma patients.Journal of neuro-oncology · 2024Article
- Improving routine use of clinical pathway decision support through integration of an EHR with a clinical library resource designed to provide evidence-based guidance within oncology workflows.BMC health services research · 2024Article
- Risk of cancer and serious disease in Danish patients with urgent referral for serious non-specific symptoms and signs of cancer in Funen 2014-2021.British journal of cancer · 2024Article
- Adopting standardized cancer patient pathways as a policy at different organizational levels in the Swedish Health System.Health research policy and systems · 2023Article
- Reduction in the diagnostic interval after the introduction of cancer patient pathways for colorectal cancer in northern Sweden.Scandinavian journal of primary health care · 2023Article
- Fast vs. Regular Track for Lung and Pancreatic Cancer Diagnosis-Time from Initial Finding to Final Diagnosis and Patient Survival.Journal of medical systems · 2023Article
- Assessing how routes to diagnosis vary by the age of patients with cancer: a nationwide register-based cohort study in Denmark.BMC cancer · 2022Article
- Routes to cancer diagnosis for patients with pre-existing psychiatric disorders: a nationwide register-based cohort study.BMC cancer · 2022Article
- Healthcare practices that increase the quality of care in cancer trajectories from a general practice perspective: a scoping review.Scandinavian journal of primary health care · 2022Article
- Equitable access to cancer patient pathways in Norway - a national registry-based study.BMC health services research · 2021Article
- Interventions to improve early cancer diagnosis of symptomatic individuals: a scoping review.BMJ open · 2021Article
- Factors influencing the delivery of cancer pathways: a summary of the literature.Journal of health organization and management · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer Patient Pathways (CPPs) were introduced in 2000-2015 in several European countries, including Denmark, to reduce the time to diagnosis and treatment initiation and ultimately improve patient survival. Yet, the prognostic consequences of implementing CPPs remain unknown for symptomatic cancer patients diagnosed through primary care. We aimed to compare survival and mortality among symptomatic patients diagnosed through a primary care route before, during and after the CPP implementation in Denmark.
methodsBased on data from the Danish Cancer in Primary Care (CaP) Cohort, we compared one- and three-year standardised relative survival (RS) and excess hazard ratios (EHRs) before, during and after CPP implementation for seven types of cancer and all combined (n = 7725) by using life-table estimation and Poisson regression. RS estimates were standardised according to the International Cancer Survival Standard (ICSS) weights. In addition, we compared RS and EHRs for CPP and non-CPP referred patients to consider potential issues of confounding by indication.
resultsIn total, 7725 cases were analysed: 1202 before, 4187 during and 2336 after CPP implementation. For all cancers combined, the RS
conclusionWe found higher relative survival and lower mortality among symptomatic cancer patients diagnosed through primary care after the implementation of CPPs in Denmark. The observed changes in cancer prognosis could be the intended consequences of finding and treating cancer at an early stage, but they may also reflect lead-time bias and selection bias. The finding of a lower excess mortality among CPP referred compared to non-CPP referred patients indicates that CPPs may have improved the cancer prognosis independently.
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