ArticleAngewandte Chemie (International ed. in English)2017
Enantioselective Catalysis Coupled with Stereodivergent Cyclization Strategies Enables Rapid Syntheses of (+)-Limaspermidine and (+)-Kopsihainanine A.
Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 66 citations in OpenAlex.
- Total syntheses of (+)-dalesconols A and B enabled by triple-relayed remote chirality transfer.Nature communications · 2026Article
- C-2 functionalization of indoles with xanthate-lactam derivatives by radical-oxidative coupling, an approach toRSC advances · 2025Article
- Total Synthesis of (+)-Hazuntiphylline, (-)-Anhydrohazuntiphyllidine, and (-)-Hazuntiphyllidine.Journal of the American Chemical Society · 2025Article
- Pd-catalyzed enantioselective access to hydrocarbazolones containing contiguous quaternary and tertiary stereocenters.Chemical science · 2025Article
- Unimolecular Fragment Coupling: A New Bond-Forming Methodology via the Deletion of Atom(s).JACS Au · 2024Review
- Enantioselective Total Synthesis of (-)-Hunterine A Enabled by a Desymmetrization/Rearrangement Strategy.Journal of the American Chemical Society · 2024Article
- Recent Advances in Chemistry and Antioxidant/Anticancer Biology of Monoterpene and Meroterpenoid Natural Product.Molecules (Basel, Switzerland) · 2024Review
- Total Synthesis of Strempeliopidine and Non-Natural Stereoisomers through a Convergent Petasis Borono-Mannich Reaction.Journal of the American Chemical Society · 2023Article
- Total Synthesis of (±)-Aspidospermidine, (±)-Aspidofractinine, (±)-Limaspermidine, and (±)-Vincadifformine via a Cascade and Common Intermediate Strategy.The Journal of organic chemistry · 2022Article
- Lithium Enolate with a Lithium-Alkyne Interaction in the Enantioselective Construction of Quaternary Carbon Centers: Concise Synthesis of (+)-Goniomitine.Angewandte Chemie (International ed. in English) · 2022Article
- Enantioselective Total Synthesis of (-)-Limaspermidine and (-)-Kopsinine by a Nitroaryl Transfer Cascade Strategy.Angewandte Chemie (International ed. in English) · 2022Article
- Total Synthesis of (-)-Voacinol and (-)-Voacandimine C.Journal of the American Chemical Society · 2022Article
- Acyclic Twisted Amides.Chemical reviews · 2021Review
- The Enantioselective Synthesis of Eburnamonine, Eucophylline, and 16'-epi-Leucophyllidine.Angewandte Chemie (International ed. in English) · 2021Article
- Recent Advances in Enantioselective Pd-Catalyzed Allylic Substitution: From Design to Applications.Chemical reviews · 2021Article
- Probing Trends in Enantioinduction via Substrate Design: Palladium-Catalyzed Decarboxylative Allylic Alkylation of α-Enaminones.Organic letters · 2020Article
- Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substitutedChemical science · 2019Article
- Direct Intermolecular Anti-Markovnikov Hydroazidation of Unactivated Olefins.Journal of the American Chemical Society · 2019Article
- The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination.ACS central science · 2018Article
- Short Enantioselective Formal Synthesis of (-)-Platencin.Synthesis · 2018Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Enantioselective Pd-catalyzed allylic alkylations of dihydropyrido[1,2-a]indolone (DHPI) substrates were used to construct the C20-quaternary stereocenters of multiple monoterpene indole alkaloids. Stereodivergent Pictet-Spengler and Bischler-Napieralski cyclization/reduction cascades furnish the cis- and trans-fused azadecalin subunits present in Aspidosperma and Kopsia alkaloids, respectively, en route to highly efficient syntheses of (+)-limaspermidine and (+)-kopsihainanine A.
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