Evidence map›Paper›PMID 28872634›Full record

ArticleScientific data2017

Advancing The Cancer Genome Atlas glioma MRI collections with expert segmentation labels and radiomic features.

Spyridon Bakas, Hamed Akbari, Aristeidis Sotiras, Michel Bilello, Martin Rozycki, Justin S Kirby, John B Freymann, Keyvan Farahani, Christos Davatzikos

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 605 papers.

0numbers the graph read from it
0cells of the map it votes in
605citing papers in PubMed
138.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

605 citing papers in PubMed, 2,817 citations in OpenAlex.

  1. Review
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  3. Invariant Texture Features to Gray Level Discretization.Journal of imaging informatics in medicine · 2026
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545 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Spyridon BakasCenter for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine, University of Pennsylvania, Richards Medical Research Laboratories, Floor 7, 3700 Hamilton Walk, Philadelphia, Pennsylvania 19104, USA.ORCID 0000-0001-8734-6482
Hamed AkbariCenter for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine, University of Pennsylvania, Richards Medical Research Laboratories, Floor 7, 3700 Hamilton Walk, Philadelphia, Pennsylvania 19104, USA.ORCID 0000-0001-9786-3707
Aristeidis SotirasCenter for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine, University of Pennsylvania, Richards Medical Research Laboratories, Floor 7, 3700 Hamilton Walk, Philadelphia, Pennsylvania 19104, USA.
Michel BilelloCenter for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine, University of Pennsylvania, Richards Medical Research Laboratories, Floor 7, 3700 Hamilton Walk, Philadelphia, Pennsylvania 19104, USA.
Martin RozyckiCenter for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine, University of Pennsylvania, Richards Medical Research Laboratories, Floor 7, 3700 Hamilton Walk, Philadelphia, Pennsylvania 19104, USA.
Justin S KirbyLeidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research (FNLCR), Cancer Imaging Program (CIP), 8560 Progress Drive, Frederick, Maryland 21701, USA.
John B FreymannLeidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research (FNLCR), Cancer Imaging Program (CIP), 8560 Progress Drive, Frederick, Maryland 21701, USA.
Keyvan FarahaniCancer Imaging Program (CIP), National Cancer Institute (NCI), 9609 Medical Center Drive, Bethesda, Maryland 20892, USA.
Christos DavatzikosCenter for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine, University of Pennsylvania, Richards Medical Research Laboratories, Floor 7, 3700 Hamilton Walk, Philadelphia, Pennsylvania 19104, USA.
University of Pennsylvania · USLeidos (United States) · USNational Cancer Institute · US

Funding

Cancer imaging phenomics software suite: application to brain and breast cancerU24CA189523 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS, KONTOS, DESPINA · 2015 to 2019
$3.2M
NCI NIH HHS U24 CA189523
6 · The paper itself

Abstract

Gliomas belong to a group of central nervous system tumors, and consist of various sub-regions. Gold standard labeling of these sub-regions in radiographic imaging is essential for both clinical and computational studies, including radiomic and radiogenomic analyses. Towards this end, we release segmentation labels and radiomic features for all pre-operative multimodal magnetic resonance imaging (MRI) (n=243) of the multi-institutional glioma collections of The Cancer Genome Atlas (TCGA), publicly available in The Cancer Imaging Archive (TCIA). Pre-operative scans were identified in both glioblastoma (TCGA-GBM, n=135) and low-grade-glioma (TCGA-LGG, n=108) collections via radiological assessment. The glioma sub-region labels were produced by an automated state-of-the-art method and manually revised by an expert board-certified neuroradiologist. An extensive panel of radiomic features was extracted based on the manually-revised labels. This set of labels and features should enable i) direct utilization of the TCGA/TCIA glioma collections towards repeatable, reproducible and comparative quantitative studies leading to new predictive, prognostic, and diagnostic assessments, as well as ii) performance evaluation of computer-aided segmentation methods, and comparison to our state-of-the-art method.

Indexed as

DNA, NeoplasmBrain NeoplasmsGliomaHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMultimodal ImagingDNA, Neoplasm

Identifiers

PMID28872634
PMCPMC5685212
OpenAlexW2751069891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.