ArticlePsychosomatic medicine2018
The Association of Posttraumatic Stress Disorder With Clinic and Ambulatory Blood Pressure in Healthy Adults.
Article in Psychosomatic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 33 citations in OpenAlex.
- Oxidative stress and impaired cardiovagal baroreflex sensitivity in young adults with post-traumatic stress disorder.Experimental physiology · 2026Article
- Individuals with posttraumatic stress disorder have increased beat-to-beat blood pressure variability.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- Posttraumatic stress disorder and hypertension in older adult Vietnam Era male and female veterans.Journal of traumatic stress · 2025Article
- Markers of Negative Emotionality in Individuals With Comorbid Alcohol Use Disorder and Post-Traumatic Stress Disorder: Role of Childhood Trauma.Addiction biology · 2025Observational
- Association of psychiatric history with hypertension among adults who present for metabolic and bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2025Article
- Cardiovascular Consequences of Posttraumatic Stress Disorder: Exaggerated Vasoconstrictor Responsiveness to Personalized Trauma Recall.Biological psychiatry · 2024Article
- Financial responsibility, financial context, and ambulatory blood pressure in early middle-aged African-American women.Social science & medicine (1982) · 2024Article
- Health insurance, perceived threat, and posttraumatic stress after suspected acute coronary syndrome.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Observational
- Investigating the associations between childhood trauma and cardiovascular health in midlife.Journal of traumatic stress · 2022Article
- Elucidating posttraumatic stress symptom dimensions and health correlates among postpartum women.Journal of affective disorders · 2021Article
- Racial and ethnic disparities in posttraumatic psychopathology among postpartum women.Journal of psychiatric research · 2021Article
- Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis.Frontiers in neuroscience · 2021Article
- How trauma influences cardiovascular responses to stress: contributions of posttraumatic stress and cognitive appraisals.Journal of behavioral medicine · 2020Article
- Duration of Perseverative Thinking as Related to Perceived Stress and Blood Pressure: An Ambulatory Monitoring Study.Psychosomatic medicine · 2019Article
- Stress-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Blockade of Angiotensin-Converting Enzyme or Tumor Necrosis Factor-α.American journal of hypertension · 2019Article
- Central nervous system neuroplasticity and the sensitization of hypertension.Nature reviews. Nephrology · 2018Review
- Experience sampling methodology in mental health research: new insights and technical developments.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018Article
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6 authors at 1 institution in 1 country.
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Abstract
objectivePosttraumatic stress disorder (PTSD) is associated with incident cardiovascular risk. We tested the association of PTSD with clinic and ambulatory blood pressure (ABP) in a sample of healthy participants and tested ABP reactivity to anxiety as a mechanism by which PTSD may influence blood pressure (BP).
methodsParticipants were originally enrolled during workplace BP screenings at three sites; approximately 6 years (standard deviation = 1.0) later, they completed nine clinic BP assessments within three visits, 1 week apart. Before the third visit, participants were screened for PTSD (≥33 on the PTSD Checklist-Civilian) and depression (Beck Depression Inventory) and then completed 24-hour ABP monitoring with electronic diary assessment of anxiety (0-100) at each awake reading.
resultsOf 440 participants, 92 (21%) screened positive for PTSD. In regression models adjusted for depression and demographic and clinical variables, PTSD was associated with greater mean systolic BP (3.8 mm Hg clinic [95% confidence interval {CI}] = 1.1-6.5, p = .006), 3.0 mm Hg awake ABP [95% CI = 0.1-5.9, p = .04], and a nonsignificant 2.1 mm Hg ABP during sleep [95% CI = -1.0 to 5.1, p = .18]). PTSD was associated with greater 24-hour median anxiety (p < .001), and changes in anxiety were positively associated with concurrent systolic ABP (p < .001). ABP reactivity to anxiety was greater in participants with PTSD, which partially explained the association of PTSD with ABP.
conclusionsPTSD is associated with greater systolic BP, partly because of greater anxiety, and systolic BP reactivity to anxiety throughout the day. Daily anxiety and related BP reactivity may be targets for interventions to reduce the cardiovascular risk associated with PTSD.
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