ArticleeLife2017
Dipolar extracellular potentials generated by axonal projections.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings.Neuron · 2025Article
- Detection of spinal action potentials with subdural electrodes in freely moving rodents.Scientific reports · 2025Article
- Single Neuron Contributions to the Auditory Brainstem EEG.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Contributions of action potentials to scalp EEG: Theory and biophysical simulations.PLoS computational biology · 2025Article
- NMDA receptor antagonist high-frequency oscillations are transmitted via bottom-up feedforward processing.Scientific reports · 2024Article
- Ultra-high density electrodes improve detection, yield, and cell type identification in neuronal recordings.bioRxiv : the preprint server for biology · 2024Article
- Efficient mapping of the thalamocortical monosynaptic connectivity in vivo by tangential insertions of high-density electrodes in the cortex.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- High-density electrode recordings reveal strong and specific connections between retinal ganglion cells and midbrain neurons.Nature communications · 2022Article
- Modelling the effect of ephaptic coupling on spike propagation in peripheral nerve fibres.Biological cybernetics · 2022Article
- Ephaptic coupling in white matter fibre bundles modulates axonal transmission delays.PLoS computational biology · 2021Article
- Neural Maps of Interaural Time Difference in the American Alligator: A Stable Feature in Modern Archosaurs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Dynamics of synaptic extracellular field potentials in the nucleus laminaris of the barn owl.Journal of neurophysiology · 2019Article
- Neural timing of stimulus events with microsecond precision.PLoS biology · 2018Article
- Contribution of action potentials to the extracellular field potential in the nucleus laminaris of barn owl.Journal of neurophysiology · 2018Article
- Multimodal Modeling of Neural Network Activity: Computing LFP, ECoG, EEG, and MEG Signals With LFPy 2.0.Frontiers in neuroinformatics · 2018Article
- Auditory brainstem response wave III is correlated with extracellular field potentials from nucleus laminaris of the barn owl.Acta acustica united with acustica : the journal of the European Acoustics Association (EEIG)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Extracellular field potentials (EFPs) are an important source of information in neuroscience, but their physiological basis is in many cases still a matter of debate. Axonal sources are typically discounted in modeling and data analysis because their contributions are assumed to be negligible. Here, we established experimentally and theoretically that contributions of axons to EFPs can be significant. Modeling action potentials propagating along axons, we showed that EFPs were prominent in the presence of terminal zones where axons branch and terminate in close succession, as found in many brain regions. Our models predicted a dipolar far field and a polarity reversal at the center of the terminal zone. We confirmed these predictions using EFPs from the barn owl auditory brainstem where we recorded in nucleus laminaris using a multielectrode array. These results demonstrate that axonal terminal zones can produce EFPs with considerable amplitude and spatial reach.
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