SynthesisEuropean journal of clinical pharmacology2017
The prevalence of medication-related adverse events in inpatients-a systematic review and meta-analysis.
Synthesis in European journal of clinical pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 4 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Hospitalizations and deaths related to adverse drug events worldwide: Systematic review of studies with national coverage.European journal of clinical pharmacology · 2022Pooled it
- Drug-related deaths among inpatients: a meta-analysis.European journal of clinical pharmacology · 2022Pooled it
- Mortality among patients due to adverse drug reactions that occur following hospitalisation: a meta-analysis.European journal of clinical pharmacology · 2019Pooled it
- Prevalence, severity, and nature of preventable patient harm across medical care settings: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2019Pooled it
- Electronic charts do not facilitate the recognition of patient hazards by advanced medical students: A randomized controlled study.PloS one · 2020Trial
- Prediction tools to prioritise hospitalised adult patients at risk of drug related problems: An umbrella review.PLOS digital health · 2026Article
- Polypharmacy and unit dose dispensing system (UDDS) in geriatric care : Challenges from the perspective of healthcare staff.Zeitschrift fur Gerontologie und Geriatrie · 2026Article
- AI-Based Automation for Medication Reconciliation: Scoping Review.Journal of medical Internet research · 2026Article
- Potentially inappropriate prescriptions in acutely admitted older patients: a development study to create a clinical decision support tool using a Delphi process.European geriatric medicine · 2026Article
- Machine learning risk prediction models for medication harm in hospitalised adult patients.Therapeutic advances in drug safety · 2026Article
- A review on adverse drug reaction related to medication in health sector: an account of what we have discovered and implemented-pharmacovigilance.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Identifying Adverse Drug Events in Clinical Text Using Fine-Tuned Clinical Language Models: Machine Learning Study.JMIR formative research · 2025Article
- Facilitators and Barriers to Uptake of Drug-Drug Interaction Alerts: Perspectives of Australian End Users and Managers.Applied clinical informatics · 2025Article
- Efficiency of computerized clinical decision support systems involving anticoagulants: A flashmob study in Dutch hospital pharmacies.British journal of clinical pharmacology · 2025Article
- Article
- Potential Adverse Drug Events Identified with Decision Support Algorithms from Janusmed Risk Profile-A Retrospective Population-Based Study in a Swedish Region.Pharmacy (Basel, Switzerland) · 2024Article
- Nurse-led medication management as a critical component of transitional care for preventing drug-related problems.Aging clinical and experimental research · 2024Review
- The use of artificial intelligence to optimize medication alerts generated by clinical decision support systems: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Identifying interventions that improve medication safety & rational use of medicines in India.The Indian journal of medical research · 2024Article
- Improving medication prescribing-related outcomes for vulnerable elderly in transitions on high-risk medications (IMPROVE-IT HRM): a pilot randomized trial protocol.Pilot and feasibility studies · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAdverse drug events (ADEs) have been internationally recognized as a major threat to patient safety. The purpose of this study was to conduct a meta-analysis focusing on inpatient ADEs in the Western World to provide better estimate of the current state of medication safety in these countries.
methodsThe studies for meta-analysis were identified through electronic search in Cochrane, Scopus, Medline, and Web of science databases. Included articles focused on adult inpatient ADEs, had commonly accepted definition for ADE, and were conducted between 2000 and 2016. Disease or ADE-specific studies were excluded. Meta-analysis was conducted on the prevalence of inpatient ADEs and fatal adverse drug reactions (FADRs).
resultsThe pooled estimate of the prevalence of inpatient ADEs was formed by 46,626 patient records included in 9 articles. Inpatient ADE prevalence was 19 and 32.3% of these ADEs were assessed preventable (MD 28.6%, SD 22.6%). Three articles including 3385 patients focused on inpatient FADRs, but the pooled estimate of this was disregarded due to low number and high heterogeneity of the included studies.
conclusionsADEs are estimated to affect 19% of inpatients during hospitalization. Most of the ADEs are moderate in severity causing no permanent harm to the patient. Only a small amount of ADEs cause inpatient deaths, but in this meta-analysis, however, we were unable to give direct estimate of the prevalence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.