Evidence map›Paper›PMID 28871393›Full record

ArticleAbdominal radiology (New York)2018

T1 vs. T2 weighted magnetic resonance imaging to assess total kidney volume in patients with autosomal dominant polycystic kidney disease.

Maatje D A van Gastel, A Lianne Messchendorp, Peter Kappert, Merel A Kaatee, Marissa de Jong, Remco J Renken, Gert J Ter Horst, Shekar V K Mahesh, Ron T Gansevoort, DIPAK Consortium

Abstract read
In one paragraph

Article in Abdominal radiology (New York), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The application of radiomics in vestibular schwannomas.The Journal of laryngology and otology · 2025
    Pooled it
  2. Trial
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  4. Kidney phosphate wasting predicts poor outcome in polycystic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Observational
  5. Article
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  7. The association of urinary epidermal growth factors with ADPKD disease severity and progression.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maatje D A van GastelDepartment of Nephrology, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.
A Lianne MesschendorpDepartment of Nephrology, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.
Peter KappertDepartment of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Merel A KaateeDepartment of Nephrology, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.
Marissa de JongDepartment of Nephrology, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.
Remco J RenkenNeuro Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Gert J Ter HorstNeuro Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Shekar V K MaheshDepartment of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Ron T GansevoortDepartment of Nephrology, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands. r.t.gansevoort@umcg.nl.
DIPAK Consortium

Funding

Dutch Government LSHM15018Nierstichting CP10.12Nierstichting CP15.01
6 · The paper itself

Abstract

purposeIn ADPKD patients total kidney volume (TKV) measurement using MRI is performed to predict rate of disease progression. Historically T1 weighted images (T1) were used, but the methodology of T2 weighted imaging (T2) has evolved. We compared the performance of both sequences.

methods40 ADPKD patients underwent an abdominal MRI at baseline and follow-up. TKV was measured by manual tracing with Analyze Direct 11.0 software. Three readers established intra- and interreader coefficients of variation (CV). T1 and T2 measured kidney volumes and growth rates were compared with ICC and Bland-Altman analyses.

resultsParticipants were 49.7 ± 7.0 years of age, 55.0% female, with estimated GFR of 50.1 ± 11.5 mL/min/1.73 m

conclusionsIn patients with ADPKD, measurement of kidney volume and growth rate performs similarly when using T2 compared to T1 weighted images, although T2 performs better on secondary outcome parameters; they are more often of sufficient quality for volume measurement and result in slightly lower intra- and interreader variability.

Indexed as

AdolescentAdultDisease ProgressionFemaleHumansKidneyMagnetic Resonance ImagingMaleMiddle AgedOrgan SizePolycystic Kidney, Autosomal DominantReproducibility of ResultsYoung AdultADPKDMRIPolycystic kidney diseaseT1T2Total kidney volume

Identifiers

PMID28871393
PMCPMC5904223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.