ArticlePediatric radiology2017
Frequency and characteristics of pulmonary nodules in children at computed tomography.
Article in Pediatric radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Pediatric pulmonary nodules: current state of knowledge, AI applications, and future directions.Pediatric radiology · 2026Review
- Lung nodules in pediatric osteosarcoma: calcification as the most reliable radiological indicator to confirm metastasis.Pediatric radiology · 2025Article
- Primary lung cancer in children and adolescents.Journal of cancer research and clinical oncology · 2024Article
- Imaging features and clinical evaluation of pulmonary nodules in children.Frontiers in oncology · 2024Article
- Imaging in rhabdomyosarcoma: a patient journey.Pediatric radiology · 2023Article
- The clinical impact of observer variability in lung nodule classification in children with Wilms tumour.Pediatric blood & cancer · 2022Article
- Ultrashort echo time MRI of the lung in children and adolescents: comparison with non-enhanced computed tomography and standard post-contrast T1w MRI sequences.European radiology · 2022Article
- Article
- Atypical pulmonary metastases in children: the spectrum of radiologic findings.Pediatric radiology · 2021Article
- Perifissural nodules: ready for application into lung cancer CT screening?Annals of translational medicine · 2020Article
- Imaging of childhood urologic cancers: current approaches and new advances.Translational andrology and urology · 2020Review
- Typical CT Features of Intrapulmonary Lymph Nodes: A Review.Radiology. Cardiothoracic imaging · 2020Review
- Measurements of cervical lymph nodes in children on computed tomography.Pediatric radiology · 2020Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundNormative data on pulmonary nodules in children without malignancy are limited. Knowledge of the frequency and characteristics of pulmonary nodules in healthy children can influence care decisions in children with malignant disease.
objectiveTo provide normative data concerning the frequency and characteristics of pulmonary nodules on computed tomography (CT) in young children. MATERIALS AND
methodsAll children ages 1 year-12 years who underwent chest CT after high-energy trauma were retrospectively investigated. Exclusion criteria were a history of malignancy, thick image slices, motion artefacts and extensive post-traumatic pulmonary changes. Two radiologists were asked to independently identify all nodules and to characterize each nodule with respect to location, size, perifissural location and calcification. Discrepancies were adjudicated by a third reader, who set the reference standard in this study. Interobserver agreement in detection and characterization was assessed using the kappa coefficient (κ).
resultsIdentified were 120 patients, of whom 72 (75% male; median age: 8.0 years [interquartile range: 4-11]) were included. A total of 59 pulmonary nodules were present in 27 patients (38%; 95% confidence interval: 26-49%; range: 1-5 nodules per patient, with a mean diameter of 3.2 mm [standard deviation: 0.9 mm]). For nodule detection, the per-patient interobserver agreement was substantial (κ=0.78) and per-lobe agreement was moderate (κ=0.40). For characterization, there was fair to substantial agreement (κ=0.36-0.74).
conclusionSmall pulmonary nodules on chest CT are a common finding in otherwise healthy children, but detection and characterization have only moderate interobserver agreement.
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