Evidence map›Paper›PMID 28871258›Full record

ArticleFrontiers in immunology2017

Distinctive Surface Glycosylation Patterns Associated With Mouse and Human CD4

Joana Cabral, Shirley A Hanley, Jared Q Gerlach, Neil O'Leary, Stephen Cunningham, Thomas Ritter, Rhodri Ceredig, Lokesh Joshi, Matthew D Griffin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Hyper α2,6-Sialylation Promotes CD4Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  11. Article
  12. Article
  13. The Role of B Cell and T Cell Glycosylation in Systemic Lupus Erythematosus.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Senescent CD4International journal of molecular sciences · 2022
    Review
  16. Dysregulated Erythroid MgFrontiers in cell and developmental biology · 2022
    Article
  17. Article
  18. Review
  19. Mechanisms of melanocyte death in vitiligo.Medicinal research reviews · 2021
    Review
  20. The Role of Glycosylation in Inflammatory Diseases.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Joana CabralRegenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, School of Medicine, College of Medicine, Nursing and Health Sciences, National University of Ireland, Galway, Ireland.
Shirley A HanleyFlow Cytometry Core Facility, National Centre for Biomedical Engineering Sciences (NCBES), National University of Ireland, Galway, Ireland.
Jared Q GerlachGlycoscience Group, National Centre for Biomedical Engineering Sciences (NCBES), National University of Ireland, Galway, Ireland.
Neil O'LearyHRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
Stephen CunninghamGlycoscience Group, National Centre for Biomedical Engineering Sciences (NCBES), National University of Ireland, Galway, Ireland.
Thomas RitterRegenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, School of Medicine, College of Medicine, Nursing and Health Sciences, National University of Ireland, Galway, Ireland.
Rhodri CeredigRegenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, School of Medicine, College of Medicine, Nursing and Health Sciences, National University of Ireland, Galway, Ireland.
Lokesh JoshiGlycoscience Group, National Centre for Biomedical Engineering Sciences (NCBES), National University of Ireland, Galway, Ireland.
Matthew D GriffinRegenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, School of Medicine, College of Medicine, Nursing and Health Sciences, National University of Ireland, Galway, Ireland.
Ollscoil na Gaillimhe – University of Galway · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory T-cells (Treg) are essential for maintaining immune homeostasis and tolerance. Surface glycosylation is ubiquitous on mammalian cells and regulates diverse biological processes. While it is currently well accepted that surface glycan expression influences multiple aspects of T-cell function, little is known about the relevance of glycosylation to Treg biology. This study aimed to profile the surface glycosylation characteristics of Treg in various lymphoid compartments of mouse and in human peripheral blood with comparison to non-regulatory, conventional CD4

Indexed as

cellular immunologyFoxp3glycosylationimmune regulationlectinsN-glycanregulatory T-cellsT cell proliferation

Identifiers

PMID28871258
PMCPMC5566562
OpenAlexW2746244293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.