Evidence map›Paper›PMID 28871198›Full record

ArticleScientific reports2017

Modulation of action potentials using PEDOT:PSS conducting polymer microwires.

Scott B Thourson, Christine K Payne

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Nanofluid-Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Scott B ThoursonInterdisciplinary Program in Bioengineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Christine K PayneSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, 30332, USA. christine.payne@chemistry.gatech.edu.
Georgia Institute of Technology · US

Funding

Conducting polymer nanowires for neural modulationR21EY026392 · NEI · GEORGIA INSTITUTE OF TECHNOLOGY · PI PAYNE, CHRISTINE K · 2015 to 2017
$453k
NEI NIH HHS R21 EY026392
6 · The paper itself

Abstract

We describe the use of PEDOT:PSS conducting polymer microwires to modulate action potentials in single cells. PEDOT: PSS conducting polymer microwires are electrochemically synthesized with diameters ranging from 860 nm to 4.5 μm and conductivities of ~30 S/cm. The length of the microwires is controlled by the spacing of the electrodes used for the electrochemical polymerization. We demonstrate the use of these microwires to control the action potentials of cardiomyocytes, showing that the cellular contractions match the frequency of the applied voltage. Membrane integrity assays confirm that the voltage delivered by the wires does not damage cells. We expect the conducting polymer microwires will be useful as minimally invasive devices to control the electrical properties of cells with high spatial precision.

Indexed as

Action PotentialsAnimalsBridged Bicyclo Compounds, HeterocyclicCell LineElectric ConductivityElectrodesHeLa CellsHumansMyocytes, CardiacNanowiresPolymersPolystyrenesRatsSingle-Cell AnalysisBridged Bicyclo Compounds, Heterocyclicpoly(3,4-ethylene dioxythiophene)PolymersPolystyrenespolystyrene sulfonic acid

Identifiers

PMID28871198
PMCPMC5583308
OpenAlexW2751398430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.