Evidence map›Paper›PMID 28871058›Full record

ArticleThe EMBO journal2017

The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription.

Amel Zouaz, Ankush Auradkar, Marie Claire Delfini, Meiggie Macchi, Marine Barthez, Serge Ela Akoa, Leila Bastianelli, Gengqiang Xie, Wu-Min Deng, Stuart S Levine and 2 more

Open access · greenAbstract read
In one paragraph

Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Amel ZouazAix Marseille Université, CNRS, IBDM, UMR 7288, Marseille, France.
Ankush AuradkarAix Marseille Université, CNRS, IBDM, UMR 7288, Marseille, France.
Marie Claire DelfiniAix Marseille Université, CNRS, IBDM, UMR 7288, Marseille, France.
Meiggie MacchiAix Marseille Université, CNRS, IBDM, UMR 7288, Marseille, France.
Marine BarthezAix Marseille Université, CNRS, IBDM, UMR 7288, Marseille, France.
Serge Ela AkoaAix Marseille Université, CNRS, IBDM, UMR 7288, Marseille, France.
Leila BastianelliMGX-Montpellier GenomiX c/o Institut de Génomique Fonctionnelle, Montpellier, France.
Gengqiang XieDepartment of Biological Science, Florida State University, Tallahassee, FL, USA.
Wu-Min DengDepartment of Biological Science, Florida State University, Tallahassee, FL, USA.
Stuart S LevineBioMicro Center, Massachusetts Institute of Technology, Cambridge, MA, USA.
Yacine GrabaAix Marseille Université, CNRS, IBDM, UMR 7288, Marseille, France.
Andrew J SaurinAix Marseille Université, CNRS, IBDM, UMR 7288, Marseille, France andrew.saurin@univ-amu.fr.ORCID 0000-0001-5162-003X
Centre National de la Recherche Scientifique · FRFlorida State University · USMassachusetts Institute of Technology · USMontpellier GenomiX · FR

Funding

Notch signaling and germline-soma interactions in the Drosophila ovarian modelR01GM072562 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI DENG, WU-MIN · 2006 to 2025
$5.6M
NIGMS NIH HHS R01 GM072562
6 · The paper itself

Abstract

In metazoans, the pausing of RNA polymerase II at the promoter (paused Pol II) has emerged as a widespread and conserved mechanism in the regulation of gene transcription. While critical in recruiting Pol II to the promoter, the role transcription factors play in transitioning paused Pol II into productive Pol II is, however, little known. By studying how

Indexed as

Gene Expression RegulationAnimalsAnimals, Genetically ModifiedCells, CulturedDrosophila melanogasterDrosophila ProteinsEmbryo, NonmammalianFemaleHomeodomain ProteinsMaleNuclear ProteinsPromoter Regions, GeneticProtein BindingRNA Polymerase IITranscription FactorsTranscription, Geneticabd-A protein, DrosophilaDrosophila ProteinsHomeodomain ProteinsM1BP protein, DrosophilaNuclear ProteinsRNA Polymerase IITranscription FactorsUbx protein, DrosophilaHoxM1BPpromoter‐proximal pausingRNA polymerase IItranscription

Identifiers

PMID28871058
PMCPMC5623858
OpenAlexW2752770712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.