Evidence map›Paper›PMID 28871039›Full record

ArticleThe Biochemical journal2017

Human TorsinA can function in the yeast cytosol as a molecular chaperone.

Ilectra Adam, Lyne Jossé, Mick F Tuite

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Biochemical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ilectra AdamKent Fungal Group, School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, U.K.
Lyne JosséKent Fungal Group, School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, U.K.
Mick F TuiteKent Fungal Group, School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, U.K. m.f.tuite@kent.ac.uk.
University of Kent · GB

Funding

Biotechnology and Biological Sciences Research Council BB/E005969/1Biotechnology and Biological Sciences Research Council BB/H012982/1
6 · The paper itself

Abstract

TorsinA (TorA) is an AAA+ (ATPases associated with diverse cellular activities) ATPase linked to dystonia type 1 (DYT1), a neurological disorder that leads to uncontrollable muscular movements. Although DYT1 is linked to a 3 bp deletion in the C-terminus of TorA, the biological function of TorA remains to be established. Here, we use the yeast

Indexed as

CytosolHumansMolecular ChaperonesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsStress, PhysiologicalMolecular ChaperonesSaccharomyces cerevisiae ProteinsTOR1A protein, humanHsp104molecular chaperoneprionSaccharomyces cerevisiaeTorsinA

Identifiers

PMID28871039
PMCPMC5628414
OpenAlexW2753562167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.