Evidence map›Paper›PMID 28871037›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Identification of Protein Tyrosine Phosphatase Receptor Type O (PTPRO) as a Synaptic Adhesion Molecule that Promotes Synapse Formation.

Wei Jiang, Mengping Wei, Mengna Liu, Yunlong Pan, Dong Cao, Xiaofei Yang, Chen Zhang

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wei JiangKey Laboratory of Cognitive Science, Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis and Treatment, Laboratory of Membrane Ion Channels and Medicine, College of Biomedical Engineering, South-Central University for Nationalities, Wuhan 430074, China.
Mengping WeiState Key Laboratory of Membrane Biology, PKU-IDG/McGovern Institute for Brain Research, School of Life Sciences, Peking University, Beijing 100871, China, and.
Mengna LiuState Key Laboratory of Membrane Biology, PKU-IDG/McGovern Institute for Brain Research, School of Life Sciences, Peking University, Beijing 100871, China, and.
Yunlong PanState Key Laboratory of Membrane Biology, PKU-IDG/McGovern Institute for Brain Research, School of Life Sciences, Peking University, Beijing 100871, China, and.
Dong CaoLaboratory Animal Center, Peking University, 5 Yiheyuan Road, Beijing 100871, China.
Xiaofei YangKey Laboratory of Cognitive Science, Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis and Treatment, Laboratory of Membrane Ion Channels and Medicine, College of Biomedical Engineering, South-Central University for Nationalities, Wuhan 430074, China, sunlittlefly@hotmail.com ch.zhang@pku.edu.cn.
Chen ZhangState Key Laboratory of Membrane Biology, PKU-IDG/McGovern Institute for Brain Research, School of Life Sciences, Peking University, Beijing 100871, China, and sunlittlefly@hotmail.com ch.zhang@pku.edu.cn.ORCID 0000-0003-1864-312X
Peking University · CNSouth Central Minzu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The proper formation of synapses-specialized unitary structures formed between two neurons-is critical to mediating information flow in the brain. Synaptic cell adhesion molecules (CAMs) are thought to participate in the initiation of the synapse formation process. However,

Indexed as

AnimalsAnimals, NewbornCoculture TechniquesExcitatory Postsynaptic PotentialsGene Knockdown TechniquesHEK293 CellsHippocampusHumansMaleMiceMice, Inbred C57BLNeural Cell Adhesion MoleculesPatch-Clamp TechniquesReceptor-Like Protein Tyrosine Phosphatases, Class 3SynapsesNeural Cell Adhesion MoleculesPtpro protein, mouseReceptor-Like Protein Tyrosine Phosphatases, Class 3co-cultureelectrophysiologymorphologicPTPROsynapse formationsynaptic cell adhesion molecules

Identifiers

PMID28871037
PMCPMC6596594
OpenAlexW2751976941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.