Evidence map›Paper›PMID 28871025›Full record

ArticleBMJ open2017

The economic impact of childhood acute gastroenteritis on Malawian families and the healthcare system.

Nathaniel Hendrix, Naor Bar-Zeev, Deborah Atherly, Jean Chikafa, Hazzie Mvula, Richard Wachepa, Amelia C Crampin, Themba Mhango, Charles Mwansambo, Robert S Heyderman and 4 more

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Quantifying the Cost ofOpen forum infectious diseases · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nathaniel HendrixCenter for Vaccine Innovation and Access, PATH, Seattle, Washington, USA.
Naor Bar-ZeevThe Centre for Global Vaccine Research, Institute of Infection & Global Health, University of Liverpool, Liverpool, Merseyside, UK.
Deborah AtherlyCenter for Vaccine Innovation and Access, PATH, Seattle, Washington, USA.
Jean ChikafaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, College of Medicine, University of Malawi, Blantyre, Malawi.
Hazzie MvulaKaronga Prevention Study, Chilumba, Malawi.
Richard WachepaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, College of Medicine, University of Malawi, Blantyre, Malawi.
Amelia C CrampinKaronga Prevention Study, Chilumba, Malawi.
Themba MhangoQueen Elizabeth Central Hospital, Blantyre, Malawi.
Charles MwansamboMinistry of Health, Lilongwe, Malawi.
Robert S HeydermanMalawi-Liverpool-Wellcome Trust Clinical Research Programme, College of Medicine, University of Malawi, Blantyre, Malawi.
Neil FrenchThe Centre for Global Vaccine Research, Institute of Infection & Global Health, University of Liverpool, Liverpool, Merseyside, UK.
Nigel A CunliffeThe Centre for Global Vaccine Research, Institute of Infection & Global Health, University of Liverpool, Liverpool, Merseyside, UK.
Clint PecenkaCenter for Vaccine Innovation and Access, PATH, Seattle, Washington, USA.
VacSurv Consortium

Funding

Wellcome Trust 098610
6 · The paper itself

Abstract

objectivesThis prospective cohort study sought to estimate health system and household costs for episodes of diarrhoeal illness in Malawi.

settingData were collected in two Malawian settings: a rural health centre in Chilumba and an urban tertiary care hospital in Blantyre.

participantsChildren under 5 years of age presenting with diarrhoeal disease between 1 January 2013 and 21 November 2014 were eligible for inclusion. Illnesses attributed to other underlying causes were excluded, as were illnesses commencing more than 2 weeks prior to presentation. Complete data were collected on 514 cases at both the time of the initial visit to the participating healthcare facility and 6 weeks after discharge. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome measure was the total cost of an episode of illness. Costs to the health system were gathered from chart review (drugs and diagnostics) and actual hospital expenditure (staff and facility costs). Household costs, including lost income, were obtained by interview with the parents/guardians of patients.

resultsTotal costs in 2014 US$ for rural inpatient, rural outpatient, urban inpatient and urban outpatient were $65.33, $8.89, $60.23 and $14.51, respectively (excluding lost income). Mean household contributions to these costs were 15.8%, 9.8%, 21.3% and 50.6%.

conclusionThis study found significant financial burden from childhood diarrhoeal disease to the healthcare system and to households. The latter face the risk of consequent impoverishment, as the study demonstrates how the costs of seeking treatment bring the income of the majority of families in all income strata below the national poverty line in the month of illness.

Indexed as

Acute DiseaseChild, PreschoolCost of IllnessFamily CharacteristicsFemaleGastroenteritisHealth Care CostsHealth ExpendituresHumansIncomeInfantLength of StayLogistic ModelsMalawiMaleProspective Studiesburden of diseasediarrheal diseasegastroenteritislow-income countriesMalawimedical impoverishment

Identifiers

PMID28871025
PMCPMC5589001

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.