Evidence map›Paper›PMID 28870972›Full record

ArticleJournal of lipid research2017

LDL cholesterol level in fifth-grade schoolchildren associates with stature.

Lee A Pyles, Christa L Lilly, Charles J Mullett, Emily S Polak, Eloise M Elliott, William A Neal

Abstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lee A PylesDepartment of Pediatrics, West Virginia University School of Medicine, Morgantown, WV lpyles@hsc.wvu.edu.
Christa L LillyDepartment of Pediatrics, West Virginia University School of Medicine, Morgantown, WV.
Charles J MullettDepartment of Pediatrics, West Virginia University School of Medicine, Morgantown, WV.
Emily S PolakDepartment of Pediatrics, West Virginia University School of Medicine, Morgantown, WV.
Eloise M ElliottCollege of Physical Education and Sports Sciences, West Virginia University School of Medicine, Morgantown, WV.
William A NealDepartment of Pediatrics, West Virginia University School of Medicine, Morgantown, WV.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

Short stature is associated with increased LDL-cholesterol levels and coronary artery disease in adults. We investigated the relationship of stature to LDL levels in children in the West Virginia Coronary Artery Risk Detection in Appalachian Communities (CARDIAC) Project to determine whether the genetically determined inverse relationship observed in adults would be evident in fifth graders. A cross-sectional survey of schoolchildren was assessed for cardiovascular risk factors. Data collected at school screenings over 18 years in WV schools were analyzed for 63,152 fifth-graders to determine relationship of LDL to stature with consideration of age, gender, and BMI. The first (shortest) quartile showed an LDL level of 93.6 mg/dl compared with an LDL level of 89.7 mg/dl for the fourth (tallest) quartile. Each incremental increase of 1 SD of height lowered LDL by 0.049 mg/dl (

Indexed as

Body HeightSchoolsChildCholesterol, LDLFemaleHumansMaleCholesterol, LDLbig datacoronary artery risk detection in Appalachian children (CARDIAC) registrygeneticslow-density lipoproteinregistry data

Identifiers

PMID28870972
PMCPMC5665673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.