Evidence map›Paper›PMID 28870312›Full record

ReviewAnalytica chimica acta2017

Recent advances in microfluidic sample preparation and separation techniques for molecular biomarker analysis: A critical review.

Mukul Sonker, Vishal Sahore, Adam T Woolley

Abstract readReview
In one paragraph

Review in Analytica chimica acta, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Review
  2. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
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  4. Article
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  8. Article
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  11. Review
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  14. Article
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  16. Review
  17. Application of microfluidic chips in anticancer drug screening.Bosnian journal of basic medical sciences · 2022
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mukul SonkerDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA.
Vishal SahoreDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA.
Adam T WoolleyDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA. Electronic address: atw@byu.edu.

Funding

Phase-Changing Sacrificial Layer Microfluidics for Enhanced Protein AnalysisR01EB006124 · NIBIB · BRIGHAM YOUNG UNIVERSITY · PI WOOLLEY, ADAM THOMAS · 2006 to 2016
$3.1M
NIBIB NIH HHS R01 EB006124
6 · The paper itself

Abstract

Microfluidics is a vibrant and expanding field that has the potential for solving many analytical challenges. Microfluidics show promise to provide rapid, inexpensive, efficient, and portable diagnostic solutions that can be used in resource-limited settings. Researchers have recently reported various microfluidic platforms for biomarker analysis applications. Sample preparation processes like purification, preconcentration and labeling have been characterized on-chip. Additionally, improvements in microfluidic separation techniques have been reported for molecular biomarkers. This review critically evaluates microfluidic sample preparation platforms and separation methods for biomarker analysis reported in the last two years. Key advances in device operation and ability to process different sample matrices in a variety of device materials are highlighted. Finally, current needs and potential future directions for microfluidic device development to realize its full diagnostic potential are discussed.

Indexed as

Microfluidic Analytical TechniquesBiomarkersLab-On-A-Chip DevicesSpecimen HandlingBiomarkersBiomarkersCapillary electrophoresisMicrofluidicsSolid-phase extraction

Identifiers

PMID28870312
PMCPMC5657502

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.