Evidence map›Paper›PMID 28870264›Full record

ArticleParasitology2018

Cryptosporidium infecting wild cricetid rodents from the subfamilies Arvicolinae and Neotominae.

Brianna L S Stenger, Michaela Horčičková, Mark E Clark, Martin Kváč, Šárka Čondlová, Eakalak Khan, Giovanni Widmer, Lihua Xiao, Catherine W Giddings, Christopher Pennil and 3 more

Open access · greenAbstract read
In one paragraph

Article in Parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Detection and Molecular Characterization ofAnimals : an open access journal from MDPI · 2023
    Article
  7. Novel genotypes ofInternational journal for parasitology. Parasites and wildlife · 2022
    Article
  8. ZoonoticMicroorganisms · 2021
    Article
  9. Microorganisms · 2021
    Article
  10. Microorganisms · 2021
    Article
  11. Parasitology · 2021
    Article
  12. Molecular Characterization ofFrontiers in veterinary science · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Brianna L S StengerDepartment of Microbiological Sciences,North Dakota State University,Fargo, ND,USA.
Michaela HorčičkováInstitute of Parasitology, Biology Centre of Czech Academy of Sciences,České Budějovice,Czech Republic.
Mark E ClarkDepartment of Biological Sciences,North Dakota State University,Fargo, ND,USA.
Martin KváčInstitute of Parasitology, Biology Centre of Czech Academy of Sciences,České Budějovice,Czech Republic.
Šárka ČondlováInstitute of Parasitology, Biology Centre of Czech Academy of Sciences,České Budějovice,Czech Republic.
Eakalak KhanEnvironmental and Conservation Sciences Program, North Dakota State University,Fargo, ND,USA.
Giovanni WidmerDepartment of Infectious Disease and Global Health,Tufts University Cummings School of Veterinary Medicine,North Grafton, MA,USA.
Lihua XiaoCenters for Disease Control and Prevention,Atlanta, GA,USA.
Catherine W GiddingsDepartment of Microbiological Sciences,North Dakota State University,Fargo, ND,USA.
Christopher PennilDepartment of Microbiological Sciences,North Dakota State University,Fargo, ND,USA.
Michal StankoSlovak Academy of Sciences,Košice,Slovakia.
Bohumil SakInstitute of Parasitology, Biology Centre of Czech Academy of Sciences,České Budějovice,Czech Republic.
John M McEvoyDepartment of Microbiological Sciences,North Dakota State University,Fargo, ND,USA.ORCID 0000-0001-6843-5551
North Dakota State University · USUniversity of South Bohemia in České Budějovice · CZCenters for Disease Control and Prevention · USInstitute of Parasitology of the Slovak Academy of Sciences · SKSlovak Academy of Sciences · SKTufts University · US

Funding

The role of host glycans in Cryptosporidium developmentR15AI122152 · NIAID · NORTH DAKOTA STATE UNIVERSITY · PI MCEVOY, JOHN M · 2016 to 2016
$483k
NIAID NIH HHS R15 AI122152
6 · The paper itself

Abstract

We undertook a study on Cryptosporidium spp. in wild cricetid rodents. Fecal samples were collected from meadow voles (Microtus pennsylvanicus), southern red-backed voles (Myodes gapperi), woodland voles (Microtus pinetorum), muskrats (Ondatra zibethicus) and Peromyscus spp. mice in North America, and from bank voles (Myodes glareolus) and common voles (Microtus arvalis) in Europe. Isolates were characterized by sequence and phylogenetic analyses of the small subunit ribosomal RNA (SSU) and actin genes. Overall, 33·2% (362/1089) of cricetids tested positive for Cryptosporidium, with a greater prevalence in cricetids from North America (50·7%; 302/596) than Europe (12·1%; 60/493). Principal Coordinate analysis separated SSU sequences into three major groups (G1-G3), each represented by sequences from North American and European cricetids. A maximum likelihood tree of SSU sequences had low bootstrap support and showed G1 to be more heterogeneous than G2 or G3. Actin and concatenated actin-SSU trees, which were better resolved and had higher bootstrap support than the SSU phylogeny, showed that closely related cricetid hosts in Europe and North America are infected with closely related Cryptosporidium genotypes. Cricetids were not major reservoirs of human pathogenic Cryptosporidium spp.

Indexed as

AnimalsAnimals, WildArvicolinaeCryptosporidiosisCryptosporidiumDisease ReservoirsEuropeFecesGenotypeMiceNorth AmericaPhylogenyPhylogeographyRNA, RibosomalRodentiaSequence Analysis, DNARNA, RibosomalbiogeographyCricetidaeCryptosporidiumphylogenetics

Identifiers

PMID28870264
PMCPMC6994186
OpenAlexW2751155262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.