Evidence map›Paper›PMID 28870248›Full record

ArticleJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2017

Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network.

Agnieszka Dzioba, Daniel Aalto, Georgina Papadopoulos-Nydam, Hadi Seikaly, Jana Rieger, Johan Wolfaardt, Martin Osswald, Jeffrey R Harris, Daniel A O'Connell, Cathy Lazarus and 12 more

Erratum issuedOpen access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 5 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Is palatal augmentation prosthesis effective in restoring speech, swallowing, and quality of life following cancer associated glossectomy? A systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  8. Influence of prosthetic rehabilitation on salivary flow, pH, and comfort sensation in patients treated for head and neck cancer.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2026
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  19. Tissue Transfer After Tongue Resection: Micro-Vascular Reconstruction Using Radial Artery Free Flap versus Reconstruction by Split Thickness Skin Graft in T2 Lesions of Tongue Carcinoma.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 3 countries.

Agnieszka DziobaDepartment of Surgery, University of Alberta Hospital, Edmonton, AB, T6G 2G4, Canada. adzioba@ualberta.ca.ORCID http://orcid.org/0000-0002-7609-5988
Daniel AaltoInstitute for Reconstructive Sciences in Medicine (iRSM), Misericordia Community Hospital, Edmonton, AB, Canada.
Georgina Papadopoulos-NydamInstitute for Reconstructive Sciences in Medicine (iRSM), Misericordia Community Hospital, Edmonton, AB, Canada.
Hadi SeikalyDepartment of Surgery, University of Alberta Hospital, Edmonton, AB, T6G 2G4, Canada.
Jana RiegerInstitute for Reconstructive Sciences in Medicine (iRSM), Misericordia Community Hospital, Edmonton, AB, Canada.
Johan WolfaardtInstitute for Reconstructive Sciences in Medicine (iRSM), Misericordia Community Hospital, Edmonton, AB, Canada.
Martin OsswaldDepartment of Surgery, University of Alberta Hospital, Edmonton, AB, T6G 2G4, Canada.
Jeffrey R HarrisDepartment of Surgery, University of Alberta Hospital, Edmonton, AB, T6G 2G4, Canada.
Daniel A O'ConnellDepartment of Surgery, University of Alberta Hospital, Edmonton, AB, T6G 2G4, Canada.
Cathy LazarusDivision of Head and Neck Surgery, Department of Otolaryngology, Head & Neck Surgery, Mount Sinai Beth Israel, New York, NY, USA.
Mark UrkenDivision of Head and Neck Surgery, Department of Otolaryngology, Head & Neck Surgery, Mount Sinai Beth Israel, New York, NY, USA.
Ilya LikhterovDivision of Head and Neck Surgery, Department of Otolaryngology, Head & Neck Surgery, Mount Sinai Beth Israel, New York, NY, USA.
Raymond L ChaiDivision of Head and Neck Surgery, Department of Otolaryngology, Head & Neck Surgery, Mount Sinai Beth Israel, New York, NY, USA.
Erika RauscherThyroid, Head And Neck Cancer (THANC) Foundation, New York, NY, USA.
Daniel BuchbinderThyroid, Head And Neck Cancer (THANC) Foundation, New York, NY, USA.
Devin OkayThyroid, Head And Neck Cancer (THANC) Foundation, New York, NY, USA.
Risto-Pekka HapponenDepartment of Oral and Maxillofacial Diseases, Turku University Hospital, Turku, Finland.
Ilpo KinnunenDepartment of Oto-Rhino-Laryngology, Turku University Hospital, Turku, Finland.
Heikki IrjalaDepartment of Oto-Rhino-Laryngology, Turku University Hospital, Turku, Finland.
Tero SoukkaDepartment of Oral and Maxillofacial Diseases, Turku University Hospital, Turku, Finland.
Juhani LaineDepartment of Oral and Maxillofacial Diseases, Turku University Hospital, Turku, Finland.
Head and Neck Research Network
University of Alberta · CAMount Sinai Beth Israel · USUniversity of Turku · FITurku University Hospital · FIAlberta Hospital Edmonton · CAThyroid Head and Neck Cancer Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile aggressive treatment for oral cancer may optimize survival, decrements in speech and swallowing function and quality of life often result. This exploratory study investigated how patients recover their communicative function, swallowing ability, and quality of life after primary surgery [with or without adjuvant (chemo)radiation therapy] for tongue cancer over the course of the first year post-operation.

methodsPatients treated for oral cancer at three institutions (University of Alberta Hospital, Mount Sinai Beth Israel Medical Center, and Turku University Hospital) were administered patient-reported outcomes assessing speech [Speech Handicap Index (SHI)], swallowing [(M.D. Anderson Dysphagia Inventory (MDADI)] and quality of life [European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Module (EORTC-H&N35)]. Outcome measures were completed pre-operatively and at 1-, 6-, and 12-months post-operatively.

resultsOne hundred and seventeen patients undergoing partial glossectomy with reconstruction participated in this study. Results indicated no significant differences in swallowing function (MDADI and EORTC-H&N35 subscales) between baseline and 6 months post-surgery and no significant differences in speech function (SHI subscales) between baseline and 1 year post-surgery. Most quality of life domains (EORTC-H&N35 subscales) returned to baseline levels by 1 year post-operation, while difficulties with dry mouth and sticky saliva persisted. A clear time trend of adjuvant (chemo)radiation therapy negatively affecting dry mouth scores over time was identified in this study, while negative independent effects of chemoradiation on MDADI swallowing, and EORTC-H&N35 swallowing, eating, and opening mouth subscales were found.

conclusionsAssessment time influenced patient-reported speech, swallowing, and quality of life outcomes, while treatment (by time) effects were found for only swallowing and quality of life outcomes. Results of the present study will help guide clinical care and will be useful for patient counseling on expected short and long-term functional and quality of life outcomes of surgical and adjuvant treatment for oral cavity cancer.

Indexed as

Activities of Daily LivingPatient Reported Outcome MeasuresAdultAgedCanadaDeglutition DisordersDisability EvaluationGlossectomyHumansLinear ModelsLongitudinal StudiesMaleMiddle AgedNeoplasm InvasivenessNeoplasm StagingPlastic Surgery ProceduresOral cancerPatient-reported outcomeQuality of lifeSpeechSwallowing

Identifiers

PMID28870248
PMCPMC5583999
OpenAlexW2751783656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.