Evidence map›Paper›PMID 28869761›Full record

ReviewImmunology2018

Novel viral vectors in infectious diseases.

Ian R Humphreys, Sarah Sebastian

Open access · hybridAbstract readReview
In one paragraph

Review in Immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 148 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. The Quest for Immunity: Exploring Human Herpesviruses as Vaccine Vectors.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Role of MHC class I pathways inFrontiers in cellular and infection microbiology · 2023
    Review

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ian R HumphreysInstitute of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, UK.ORCID 0000-0002-9512-5337
Sarah SebastianThe Jenner Institute, University of Oxford, Oxford, UK.ORCID 0000-0001-7918-4321
University of Oxford · GBWellcome Sanger Institute · GB

Funding

Wellcome Trust 207503/Z/17/Z
6 · The paper itself

Abstract

Since the development of vaccinia virus as a vaccine vector in 1984, the utility of numerous viruses in vaccination strategies has been explored. In recent years, key improvements to existing vectors such as those based on adenovirus have led to significant improvements in immunogenicity and efficacy. Furthermore, exciting new vectors that exploit viruses such as cytomegalovirus (CMV) and vesicular stomatitis virus (VSV) have emerged. Herein, we summarize these recent developments in viral vector technologies, focusing on novel vectors based on CMV, VSV, measles and modified adenovirus. We discuss the potential utility of these exciting approaches in eliciting protection against infectious diseases.

Indexed as

Communicable Disease ControlAdaptive ImmunityAnimalsCommunicable DiseasesGenetic VectorsHumansVaccinationVaccines, SyntheticViral VaccinesVirusesVaccines, SyntheticViral VaccinesmemoryT cellvaccinationviral

Identifiers

PMID28869761
PMCPMC5721250
OpenAlexW2752960590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.