ReviewInternational journal of environmental research and public health2017
Gene Drive for Mosquito Control: Where Did It Come from and Where Are We Headed?
Review in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed.
- Advancing Malaria Vector Control: Insights Into Mosquito Immunity and Genetic Strategies.TheScientificWorldJournal · 2026Review
- Cryopreservation of Anopheles gambiae Larvae.Advanced biology · 2026Article
- Crystal Structure of Autophagy-Associated Protein 8 at 1.36 Å Resolution and Its Inhibitory Interactions with Indole Analogs.Journal of agricultural and food chemistry · 2025Article
- Cas9/guide RNA-based gene-drive dynamics following introduction and introgression into diverse anopheline mosquito genetic backgrounds.BMC genomics · 2024Article
- Next-generation neuropeptide Y receptor small-molecule agonists inhibit mosquito-biting behavior.Parasites & vectors · 2024Article
- Article
- ROY Crystallization on Poly(ethylene) Fibers, a Model for Bed Net Crystallography.Chemistry of materials : a publication of the American Chemical Society · 2024Article
- Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior.bioRxiv : the preprint server for biology · 2024Article
- Importance ofBiosafety and health · 2023Review
- A gene drive is a gene drive: the debate over lumping or splitting definitions.Nature communications · 2023Article
- Expression of anti-chikungunya single-domain antibodies in transgenicFrontiers in microbiology · 2023Article
- Slow and steady wins the race: Spatial and stochastic processes and the failure of suppression gene drives.Molecular ecology · 2022Article
- The AalNix3&4 isoform is required and sufficient to convert Aedes albopictus females into males.PLoS genetics · 2022Article
- A Conserved Female-Specific Requirement for thePathogens (Basel, Switzerland) · 2022Article
- Recent advancement in VM task allocation system for cloud computing: review from 2015 to2021.Artificial intelligence review · 2022Article
- Seminal fluid proteins induce transcriptome changes in the Aedes aegypti female lower reproductive tract.BMC genomics · 2021Article
- Mosquito control at a tertiary teaching hospital in Nigeria.Infection prevention in practice · 2021Article
- Sexual selection theory meets disease vector control: Testing harmonic convergence as a "good genes" signal in Aedes aegypti mosquitoes.PLoS neglected tropical diseases · 2021Article
- The impact of artificial selection for Wolbachia-mediated dengue virus blocking on phage WO.PLoS neglected tropical diseases · 2021Article
- A conserved female-specific larval requirement for MtnB function facilitates sex separation in multiple species of disease vector mosquitoes.Parasites & vectors · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Mosquito-borne pathogens place an enormous burden on human health. The existing toolkit is insufficient to support ongoing vector-control efforts towards meeting disease elimination and eradication goals. The perspective that genetic approaches can potentially add a significant set of tools toward mosquito control is not new, but the recent improvements in site-specific gene editing with CRISPR/Cas9 systems have enhanced our ability to both study mosquito biology using reverse genetics and produce genetics-based tools. Cas9-mediated gene-editing is an efficient and adaptable platform for gene drive strategies, which have advantages over innundative release strategies for introgressing desirable suppression and pathogen-blocking genotypes into wild mosquito populations; until recently, an effective gene drive has been largely out of reach. Many considerations will inform the effective use of new genetic tools, including gene drives. Here we review the lengthy history of genetic advances in mosquito biology and discuss both the impact of efficient site-specific gene editing on vector biology and the resulting potential to deploy new genetic tools for the abatement of mosquito-borne disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.