Evidence map›Paper›PMID 28869492›Full record

ArticleInternational journal of molecular sciences2017

The Lactate/Albumin Ratio: A Valuable Tool for Risk Stratification in Septic Patients Admitted to ICU.

Michael Lichtenauer, Bernhard Wernly, Bernhard Ohnewein, Marcus Franz, Bjoern Kabisch, Johanna Muessig, Maryna Masyuk, Alexander Lauten, Paul Christian Schulze, Uta C Hoppe and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Prioritized factors of severity prognosis in patients admitted for sepsis or septic shock in a resource-limited region of central Vietnam.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026
    Article
  8. Anesthetic management and early outcomes in patients with earthquake-induced crush and compartment syndrome: A single-center retrospective an.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michael LichtenauerClinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria. m.lichtenauer@salk.at.
Bernhard WernlyClinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria. b.wernly@salk.at.
Bernhard OhneweinClinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria. b.ohnewein@salk.at.
Marcus FranzClinic of Internal Medicine I, Department of Cardiology, Jena University Hospital, 07747 Jena, Germany. Marcus.Franz@med.uni-jena.de.
Bjoern KabischClinic of Internal Medicine I, Department of Cardiology, Jena University Hospital, 07747 Jena, Germany. Bjoern.Kabisch@med.uni-jena.de.
Johanna MuessigDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany. Johanna.Muessig@med.uni-duesseldorf.de.
Maryna MasyukDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany. Maryna.Masyuk@med.uni-duesseldorf.de.
Alexander LautenDepartment of Cardiology, Charité-Universitaetsmedizin Berlin, 12203 Berlin, Germany. Alexander.Lauten@charite.de.
Paul Christian SchulzeClinic of Internal Medicine I, Department of Cardiology, Jena University Hospital, 07747 Jena, Germany. Christian.Schulze@med.uni-jena.de.
Uta C HoppeClinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria. u.hoppe@salk.at.
Malte KelmDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany. malte.kelm@med.uni-duesseldorf.de.
Christian JungDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany. christian.jung@med.uni-duesseldorf.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lactate/albumin ratio has been reported to be associated with mortality in pediatric patients with sepsis. We aimed to evaluate the lactate/albumin ratio for its prognostic relevance in a larger collective of critically ill (adult) patients admitted to an intensive care unit (ICU). A total of 348 medical patients admitted to a German ICU for sepsis between 2004 and 2009 were included. Follow-up of patients was performed retrospectively between May 2013 and November 2013. The association of the lactate/albumin ratio (cut-off 0.15) and both in-hospital and post-discharge mortality was investigated. An optimal cut-off was calculated by means of Youden's index. The lactate/albumin ratio was elevated in non-survivors (

Indexed as

Serum AlbuminAgedBiomarkersCase-Control StudiesCritical IllnessHospital MortalityHumansIntensive Care UnitsLactic AcidMiddle AgedPrognosisROC CurveSepsisSeverity of Illness IndexBiomarkersLactic AcidSerum Albuminalbumincritically ill patientsICUlactatelactate/albumin ratiorisk scorerisk stratification

Identifiers

PMID28869492
PMCPMC5618542

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.