Evidence map›Paper›PMID 28868974›Full record

ArticleNeurorehabilitation and neural repair

Brain Changes Following Executive Control Training in Older Adults.

Areeba Adnan, Anthony J W Chen, Tatjana Novakovic-Agopian, Mark D'Esposito, Gary R Turner

Open access · bronzeAbstract read
In one paragraph

Article in Neurorehabilitation and neural repair. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Areeba Adnan1 York University, Toronto, Ontario, Canada.
Anthony J W Chen2 Veteran's Administration Northern California Health Care System, Martinez, CA, USA.
Tatjana Novakovic-Agopian2 Veteran's Administration Northern California Health Care System, Martinez, CA, USA.
Mark D'Esposito2 Veteran's Administration Northern California Health Care System, Martinez, CA, USA.
Gary R Turner1 York University, Toronto, Ontario, Canada.
VA Northern California Health Care System · USYork University · CAUniversity of California, Berkeley · US

Funding

A Brain-based Approach to Enhancing Executive Control Functions in Healthy AgingR01AG034642 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI D'ESPOSITO, MARK · 2009 to 2011
$790k
Rehabilitation of Executive Functioning in Veterans with PTSD and Mild TBII01RX001111 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI NOVAKOVIC-AGOPIAN, TATJANA · 2015 to 2017
–
NIA NIH HHS R01 AG034642RRD VA I01 RX001111
6 · The paper itself

Abstract

backgroundWhile older adults are able to attend to goal-relevant information, the capacity to ignore irrelevant or distracting information declines with advancing age. This decline in selective attention has been associated with poor modulation of brain activity in sensory cortices by anterior brain regions implicated in cognitive control.

objectiveHere we investigated whether participation in an executive control training program would result in improved selective attention and associated functional brain changes in a sample of healthy older adults (N = 24, age 60-85 years).

methodsParticipants were enrolled in a goal-oriented attentional self-regulation (GOALS) program (n = 11) or a brain health education workshop as an active control condition (n = 13). All participants performed a working memory task requiring attention to or suppression of visual stimuli based on goal-relevance during functional magnetic resonance imaging.

resultsWe observed a pattern of enhanced activity in right frontal, parietal and temporal brain regions from pre- to posttraining in the GOALS intervention group, which predicted the selectivity of subsequent memory for goal-relevant stimuli.

conclusionsExecutive control training in older adults alters functional activity in brain regions associated with attentional control, and selectively predicts behavioral outcome.

Indexed as

GoalsTeachingAgedAged, 80 and overAge FactorsAgingAttentionBrainExecutive FunctionFemaleFunctional LateralityHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemoryOxygenagingattentionexecutive functionfMRIrehabilitationtraining

Identifiers

PMID28868974
PMCPMC5729113
OpenAlexW2751102514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.