Evidence map›Paper›PMID 28868513›Full record

ArticleKidney international reports2017

Evaluation of Renal Blood Flow in Chronic Kidney Disease Using Arterial Spin Labeling Perfusion Magnetic Resonance Imaging.

Lu-Ping Li, Huan Tan, Jon M Thacker, Wei Li, Ying Zhou, Orly Kohn, Stuart M Sprague, Pottumarthi V Prasad

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Arterial spin labelling MRI to measure renal perfusion: a systematic review and statement paper.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2018
    Pooled it
  2. Renal blood flow and progression to kidney failure in ADPKD.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Observational
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  14. A PopPBPK-RL approach for precision dosing of benazepril in renal impaired patients.Journal of pharmacokinetics and pharmacodynamics · 2024
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  17. Native TiScience · 2024
    Article
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  20. Radiology of fibrosis part III: genitourinary system.Journal of translational medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lu-Ping LiCenter for Advanced Imaging, NorthShore University HealthSystem, Evanston, IL.
Huan TanCenter for Advanced Imaging, NorthShore University HealthSystem, Evanston, IL.
Jon M ThackerDepartment of Biomedical Engineering, Northwestern University, Evanston, IL.
Wei LiCenter for Advanced Imaging, NorthShore University HealthSystem, Evanston, IL.
Ying ZhouCenter for Biomedical Research & Informatics, NorthShore University HealthSystem, Evanston, IL.
Orly KohnDepartment of Nephrology, University of Chicago, Chicago, IL.
Stuart M SpragueDepartment of Nephrology, NorthShore University HealthSystem, Evanston, IL.
Pottumarthi V PrasadCenter for Advanced Imaging, NorthShore University HealthSystem, Evanston, IL.
NorthShore University HealthSystem · USUniversity of Chicago · USNorthwestern University · US

Funding

Longitudinal changes in the intra-renal oxygenation by BOLD MRI in patients withR01DK093793 · NIDDK · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI PRASAD, POTTUMARTHI V · 2012 to 2016
$2.3M
The Intra-renal Oxygenation in CKD as evaluated by BOLD MRIR21DK079080 · NIDDK · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI PRASAD, POTTUMARTHI V · 2009 to 2010
$431k
Quantitative renal oxygenation assessment with compartment specific calibrationF31HL123360 · NHLBI · NORTHWESTERN UNIVERSITY · PI THACKER, JON MATTHEW · 2015 to 2016
$70k
NHLBI NIH HHS F31 HL123360NIDDK NIH HHS R01 DK093793NIDDK NIH HHS R21 DK079080
6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) is known to be associated with reduced renal blood flow. However, data to-date in humans is limited.

methodsIn this study, non-invasive arterial spin labeling (ASL) MRI data was acquired in 33 patients with diabetes and stage-3 CKD, and 30 healthy controls.

resultsA significantly lower renal blood flow both in cortex (108.4±36.4

conclusionThese results support the use of ASL in the evaluation of renal blood flow in patients with moderate level of CKD. Whether these measurements can identify subjects at risk of progressive CKD requires further longitudinal follow-up.

Indexed as

arterial spin labelingchronic kidney diseaseeGFRMRIperfusionrenal blood flow

Identifiers

PMID28868513
PMCPMC5575771
OpenAlexW2520348885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.