ArticleBiomicrofluidics2017
Rapid evaporation-driven chemical pre-concentration and separation on paper.
Article in Biomicrofluidics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 19 citations in OpenAlex.
- Solvent-pumped evaporation concentration on paper in linear and radial geometries.Biomicrofluidics · 2023Article
- Paper-based evaporation concentrators: Comparison of linear and radial geometries.Biomicrofluidics · 2023Article
- Microfluidic Time-Delay Valve Mechanism on Paper-Based Devices for Automated Competitive ELISA.Micromachines · 2019Article
- Novel Variable Radius Spiral⁻Shaped Micromixer: From Numerical Analysis to Experimental Validation.Micromachines · 2018Article
- Estimation of Effective Fracture Aperture in Glacial Tills by Analysis of Dye Tracer Penetration.Ground waterArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Airflow-enhanced evaporation is investigated as a method for rapid chemical preconcentration on a thin porous substrate. The mechanism is described by combining 1D models of capillary rise, chromatography, and pervaporation concentration. It is shown that the effective length of the column can be shorter than its actual length, allowing concentrate to be held at a stagnation point and then released for separation, and that the Péclet number, which determines the concentration performance, is determined only by the substrate properties. The differential equations are solved dynamically, and it is shown that faster concentration can be achieved during capillary filling. Experiments are carried out using chromatography paper in a ducted airflow, and concentration is quantified by optical imaging of water-soluble food dyes. Good agreement with the model is obtained, and concentration factors of ≈100 are achieved in 10 min using Brilliant Blue FCF. Partial separation of Brilliant Blue from Tartrazine is demonstrated immediately following concentration, on a single unpatterned substrate. The mechanism may provide a method for improving the sensitivity of lab-on-paper devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.