Evidence map›Paper›PMID 28868036›Full record

ArticleFrontiers in pharmacology2017

Baicalin Alleviates Lipopolysaccharide-Induced Liver Inflammation in Chicken by Suppressing TLR4-Mediated NF-κB Pathway.

Ping Cheng, Tong Wang, Wei Li, Ishfaq Muhammad, He Wang, Xiaoqi Sun, Yuqi Yang, Jiarui Li, Tianshi Xiao, Xiuying Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Anti-Inflammatory Activity ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Veterinary sciences · 2025
    Review
  13. Article
  14. Hepatoprotective Effect of Kaempferol-A Review.Molecules (Basel, Switzerland) · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Frontiers in pharmacology · 2025
    Review
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ping ChengDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Tong WangDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Wei LiDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Ishfaq MuhammadDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
He WangDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Xiaoqi SunDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Yuqi YangDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Jiarui LiDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Tianshi XiaoDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Xiuying ZhangDepartment of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural UniversityHarbin, China.
Northeast Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a kind of potent stimulus, lipopolysaccharide (LPS) has the ability to cause cell damage by activating toll-like receptor(TLR)4, then nuclear factor kappa B (NF-κB) translocates into the nucleus and changes the expression of related inflammatory genes. Baicalin is extracted from

Indexed as

anti-inflammationBaicalinlipopolysaccharideliver inflammationNF-κBTLR4

Identifiers

PMID28868036
PMCPMC5563358
OpenAlexW2745854656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.