Evidence map›Paper›PMID 28867858›Full record

ArticleAncient science of life

Evaluation of Cyavanaprāśa on Health and Immunity related Parameters in Healthy Children: A Two Arm, Randomized, Open Labeled, Prospective, Multicenter, Clinical Study.

Arun Gupta, Sunil Kumar, Sanjeeva Dole, Shailesh Deshpande, Vaishali Deshpande, Sudha Singh, V Sasibhushan

Open access · diamondAbstract read
In one paragraph

Article in Ancient science of life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Golden Ager Chyawanprash with Meager Evidential Base from Human Clinical Trials.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Ayurveda: (W)here is the evidence.Journal of Ayurveda and integrative medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Arun GuptaDabur Research and Development Centre, Ghaziabad, Uttar Pradesh, India.
Sunil KumarDabur Research and Development Centre, Ghaziabad, Uttar Pradesh, India.
Sanjeeva DoleDepartment of Kaumarbhrtya, Sumati Shah Ayurvedic Hospital, Pune, Maharashtra, India.
Shailesh DeshpandePDEA's College of Ayurveda and Research Centre, Pune, Maharashtra, India.
Vaishali DeshpandeDepartment of Kaumarbhrtya, Sumati Shah Ayurvedic Hospital, Pune, Maharashtra, India.
Sudha SinghPDEA's College of Ayurveda and Research Centre, Pune, Maharashtra, India.
V SasibhushanDabur Research and Development Centre, Ghaziabad, Uttar Pradesh, India.
Dabur (India) · INGovernment Ayurved College, Nanded · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextCyavanaprāśa (CP) is an Ayurvedic immune booster formulation that confers vigor and vitality while delaying the ageing process. Benefits of CP have been studied widely in adult population.

objectivesCurrent study assessed beneficial effects of CP on health and immunity related parameters in healthy children.

methodsThis study was a 6 month long two armed, randomized, open labeled, prospective clinical study. School going healthy children between ages of 5-12 years were randomized to receive orally daily either CP (approx. 6 g) followed by a cup of milk (100 - 200 ml) or cup of milk only twice a day while continuing with their normal/routine diet. Results were analyzed based on number of episodes, severity, duration of illness (infections and allergies) and number of absent days due to illness during the study duration and changes in levels of energy, physical fitness, strength, stamina and quality of life in children which were recorded in subject diary by their parents/Legally Acceptable Representative (LAR).

results702 participants were randomized, out of which 627 completed the study (CP n = 313; Control n = 314). Results of immunity (episodes of infections or allergy related conditions) showed more than 2 times protection from immunity related illness in CP Group as compared to the control. CP also showed better percentage improvement in energy levels, physical fitness, strength, stamina and quality of life assessed through KIDSCREEN QOL-27 questionnaires in children.

conclusionRegular consumption of CP for a period of six months could significantly improve immunity, energy levels, physical fitness, strength, stamina and quality of life in school going healthy children. STUDY REGISTRATION: Clinical Trail Registry of India

Indexed as

AllergychildrenchyawanprashimmunityinfectionKIDSCREEN-27 questionnairestaminastrength

Identifiers

PMID28867858
PMCPMC5566825
OpenAlexW2742390596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.