Evidence map›Paper›PMID 28867843›Full record

ArticleBulletin of the World Health Organization2017

Estimated economic impact of vaccinations in 73 low- and middle-income countries, 2001-2020.

Sachiko Ozawa, Samantha Clark, Allison Portnoy, Simrun Grewal, Meghan L Stack, Anushua Sinha, Andrew Mirelman, Heather Franklin, Ingrid K Friberg, Yvonne Tam and 11 more

Open access · diamondAbstract read
In one paragraph

Article in Bulletin of the World Health Organization, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 7 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 7 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. Pooled it
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  5. A need to raise the bar - A systematic review of temporal trends in diagnostics for Japanese encephalitis virus infection, and perspectives for future research.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
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  17. Vaccines in cancer treatment and prevention: the time is now.The Journal of clinical investigation · 2025
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 4 countries.

Sachiko OzawaDivision of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, CB # 7574, Beard Hall 115H, Chapel Hill, North Carolina, 27599, United States of America (USA).
Samantha ClarkDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Allison PortnoyDepartment of Global Health and Population, Harvard TH Chan School of Public Health, Boston, USA.
Simrun GrewalDepartment of Pharmacy, University of Washington, Seattle, USA.
Meghan L StackIndependent Consultant, Denver, USA.
Anushua SinhaDepartment of Preventive Medicine and Community Health, Rutgers New Jersey Medical School, Newark, USA.
Andrew MirelmanCentre for Health Economics, University of York, York, England.
Heather FranklinDepartment of Preventive Medicine and Community Health, Rutgers New Jersey Medical School, Newark, USA.
Ingrid K FribergDepartment of Health Services, Norwegian Institute of Public Health, Oslo, Norway.
Yvonne TamDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Neff WalkerDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Andrew ClarkDepartment of Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, England.
Matthew FerrariCenter for Infectious Disease Dynamics, The Pennsylvania State University, University Park, USA.
Chutima SuraratdechaIndependent Consultant, Vienna, USA.
Steven SweetCenter for Health Decision Science, Harvard TH Chan School of Public Health, Boston, USA.
Sue J GoldieCenter for Health Decision Science, Harvard TH Chan School of Public Health, Boston, USA.
Tini GarskeMRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, England.
Michelle LiGavi, the Vaccine Alliance, Geneva, Switzerland.
Peter M HansenThe Global Fund to Fight AIDS, Tuberculosis and Malaria, Geneva, Switzerland.
Hope L JohnsonGavi, the Vaccine Alliance, Geneva, Switzerland.
Damian WalkerBill & Melinda Gates Foundation, Seattle, USA.
Johns Hopkins University · USGavi · CHRutgers, The State University of New Jersey · USBill & Melinda Gates Foundation · USGlobal Fund to Fight AIDS, Tuberculosis and Malaria · CHHarvard Global Health Institute · USLondon School of Hygiene & Tropical Medicine · GBNorwegian Institute of Public Health · NOPennsylvania State University · USSeattle University · USUniversity of York · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate the economic impact likely to be achieved by efforts to vaccinate against 10 vaccine-preventable diseases between 2001 and 2020 in 73 low- and middle-income countries largely supported by Gavi, the Vaccine Alliance.

methodsWe used health impact models to estimate the economic impact of achieving forecasted coverages for vaccination against

findingsWe estimated that, in the 73 countries, vaccinations given between 2001 and 2020 will avert over 20 million deaths and save US$ 350 billion in cost of illness. The deaths and disability prevented by vaccinations given during the two decades will result in estimated lifelong productivity gains totalling US$ 330 billion and US$ 9 billion, respectively. Over the lifetimes of the vaccinated cohorts, the same vaccinations will save an estimated US$ 5 billion in treatment costs. The broader economic and social value of these vaccinations is estimated at US$ 820 billion.

conclusionBy preventing significant costs and potentially increasing economic productivity among some of the world's poorest countries, the impact of immunization goes well beyond health.

Indexed as

Cost of IllnessCommunicable Disease ControlCommunicable DiseasesCost-Benefit AnalysisDeveloping CountriesGlobal HealthHumansImmunization ProgramsMonte Carlo MethodQuality-Adjusted Life YearsVaccinationVaccinesVaccines

Identifiers

PMID28867843
PMCPMC5578376
OpenAlexW2752353918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.