Evidence map›Paper›PMID 28867783›Full record

ReviewViruses2017

The Mouse Papillomavirus Infection Model.

Jiafen Hu, Nancy M Cladel, Lynn R Budgeon, Karla K Balogh, Neil D Christensen

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Journal of virology · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Cutaneous papillomaviruses infection rewires fatty-acid metabolism.Frontiers in cellular and infection microbiology · 2026
    Article
  10. bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Papillomavirus-like particles as vectors forMolecular therapy. Nucleic acids · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Deficiency inJournal of virology · 2024
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiafen HuThe Jake Gittlen Laboratories for Cancer Research, Hershey, PA 17033, USA. fjh4@psu.edu.
Nancy M CladelThe Jake Gittlen Laboratories for Cancer Research, Hershey, PA 17033, USA. ncladel@gmail.com.
Lynn R BudgeonThe Jake Gittlen Laboratories for Cancer Research, Hershey, PA 17033, USA. lrb11@psu.edu.
Karla K BaloghThe Jake Gittlen Laboratories for Cancer Research, Hershey, PA 17033, USA. kkb2@psu.edu.
Neil D ChristensenThe Jake Gittlen Laboratories for Cancer Research, Hershey, PA 17033, USA. ndc1@psu.edu.
Hershey (United States) · US

Funding

Role of estrous cycle and contraceptives in anogenital papillomavirus infectionR21AI121822 · NIAID · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CHRISTENSEN, NEIL D, HU, JIAFEN · 2016 to 2017
$425k
NIAID NIH HHS R21 AI121822
6 · The paper itself

Abstract

The mouse papillomavirus (MmuPV1) was first reported in 2011 and has since become a powerful research tool. Through collective efforts from different groups, significant progress has been made in the understanding of molecular, virological, and immunological mechanisms of MmuPV1 infections in both immunocompromised and immunocompetent hosts. This mouse papillomavirus provides, for the first time, the opportunity to study papillomavirus infections in the context of a small common laboratory animal for which abundant reagents are available and for which many strains exist. The model is a major step forward in the study of papillomavirus disease and pathology. In this review, we summarize studies using MmuPV1 over the past six years and share our perspectives on the value of this unique model system. Specifically, we discuss viral pathogenesis in cutaneous and mucosal tissues as well as in different mouse strains, immune responses to the virus, and local host-restricted factors that may be involved in MmuPV1 infections and associated disease progression.

Indexed as

Disease Models, AnimalAdaptive ImmunityAnimalsB-LymphocytesDisease ProgressionHumansImmunity, InnateMiceMouth DiseasesMucous MembranePapillomaviridaePapillomavirus InfectionsSequence Analysis, RNASkinSkin NeoplasmsT-Lymphocytesadaptive immunityanogenitalhost defenseinnate immunityoral infectionpathogenesisRNA sequencingskin carcinomathe mouse papillomavirustissue tropism

Identifiers

PMID28867783
PMCPMC5618012
OpenAlexW2752724784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.