Evidence map›Paper›PMID 28867591›Full record

ArticleVascular pharmacology2017

Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced nitric oxide production and vasorelaxation in rabbit mesenteric arteries.

Harry Z E Greenberg, Simonette R E Carlton-Carew, Dhanak M Khan, Alexander K Zargaran, Kazi S Jahan, W-S Vanessa Ho, Anthony P Albert

Open access · hybridAbstract read
In one paragraph

Article in Vascular pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Role of the calcium-sensing receptor in regulating vascular function.Journal of cell communication and signaling · 2025
    Review
  5. Review
  6. Article
  7. Mechanosensory entities and functionality of endothelial cells.Frontiers in cell and developmental biology · 2024
    Review
  8. Article
  9. Lysosomal TRPML1 triggers global CaFrontiers in physiology · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Transient Receptor Potential (TRP) Channels in Tumor Vascularization.International journal of molecular sciences · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Harry Z E GreenbergVascular Biology Research Centre, Molecular & Clinical Sciences Research Institute, St. George's, University of London, Cranmer Terrace, London SW17 0RE, UK. Electronic address: harry.greenberg@gmail.com.
Simonette R E Carlton-CarewVascular Biology Research Centre, Molecular & Clinical Sciences Research Institute, St. George's, University of London, Cranmer Terrace, London SW17 0RE, UK.
Dhanak M KhanVascular Biology Research Centre, Molecular & Clinical Sciences Research Institute, St. George's, University of London, Cranmer Terrace, London SW17 0RE, UK.
Alexander K ZargaranVascular Biology Research Centre, Molecular & Clinical Sciences Research Institute, St. George's, University of London, Cranmer Terrace, London SW17 0RE, UK.
Kazi S JahanVascular Biology Research Centre, Molecular & Clinical Sciences Research Institute, St. George's, University of London, Cranmer Terrace, London SW17 0RE, UK.
W-S Vanessa HoVascular Biology Research Centre, Molecular & Clinical Sciences Research Institute, St. George's, University of London, Cranmer Terrace, London SW17 0RE, UK.
Anthony P AlbertVascular Biology Research Centre, Molecular & Clinical Sciences Research Institute, St. George's, University of London, Cranmer Terrace, London SW17 0RE, UK.
St George's, University of London · GB

Funding

Biotechnology and Biological Sciences Research CouncilBritish Heart Foundation FS/13/10/30021British Heart Foundation FS/15/44/31570British Heart Foundation FS/17/40/32942
6 · The paper itself

Abstract

Stimulation of calcium-sensing receptors (CaSR) by increasing the external calcium concentration (Ca

Indexed as

VasodilationAnimalsCalcium SignalingDose-Response Relationship, DrugEndothelial CellsIn Vitro TechniquesMaleMembrane PotentialsMesenteric Artery, SuperiorNitric OxideRabbitsReceptors, Calcium-SensingTRPC Cation ChannelsTRPV Cation ChannelsVasodilator AgentsNitric OxideReceptors, Calcium-Sensingtransient receptor potential cation channel, subfamily C, member 1TRPC Cation ChannelsTRPV Cation ChannelsVasodilator Agents

Identifiers

PMID28867591
PMCPMC5614111
OpenAlexW2753183371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.