Evidence map›Paper›PMID 28867295›Full record

ReviewChest2018

Asthma Outcomes and Management During Pregnancy.

Catherine A Bonham, Karen C Patterson, Mary E Strek

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Chest, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05047419 (Using Mobile Health Approaches to Improve Asthma Treatment), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05047419 completednot on this mapstarted 2021, after this paper: background citation

Using Mobile Health Approaches to Improve Asthma Treatment

TypeobservationalSponsorLinnea PolgreenRan2021 to 2023Enrolled83ConditionsAsthma, Pregnancy
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Obesity and asthma during pregnancy: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  3. Article
  4. Medication use during pregnancy in Japan from 2005 to 2019: Trends and safety considerations.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Treatable Traits in Pregnant Women with Asthma.Respiration; international review of thoracic diseases · 2024
    Review
  17. Observational
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Catherine A BonhamSection of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL. Electronic address: catherine.bonham@uchospitals.edu.
Karen C PattersonDivision of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA; Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom.
Mary E StrekSection of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL.
University of Chicago · USUniversity of Pennsylvania · US

Funding

RESEARCH TRAINING IN RESPIRATORY BIOLOGYT32HL007605 · NHLBI · UNIVERSITY OF CHICAGO · PI Yun Fang, Gokhan M. Mutlu · 1985 to 2026
$18.1M
Training of Junior Faculty for Careers in Omics of Lung DiseasesK12HL119995 · NHLBI · UNIVERSITY OF CHICAGO · PI GOZAL, DAVID, GROSSMAN, ROBERT L. · 2013 to 2017
$1.3M
NHLBI NIH HHS K12 HL119995NHLBI NIH HHS T32 HL007605
6 · The paper itself

Abstract

Asthma during pregnancy poses a common, increasingly prevalent threat to the health of women and their children. The present article reviews recent insights gained from the epidemiology of asthma during pregnancy, demonstrating the many short- and long-term risks to mother and fetus incurred by poorly controlled maternal asthma. We further discuss emerging evidence that active management of asthma during pregnancy can positively influence and perhaps completely mitigate these poor outcomes. Recent high-quality trials examining best methods for asthma treatment are reviewed and synthesized to offer an evidence-based pathway for comprehensive treatment of asthma in the outpatient setting. Safe and effective medications, as well as nonpharmacologic interventions, for asthma during pregnancy are discussed, and treatment options for related conditions of pregnancy, including depression, rhinitis, and gastroesophageal reflux, are presented. Throughout, we emphasize that an effective treatment strategy relies on a detailed patient evaluation, patient education, objective measurement of asthma control, and frequent and supportive follow-up. The cardiovascular and respiratory physiology of pregnancy is reviewed, as well as its implications for the management of patients with asthma, including patients requiring intubation and mechanical ventilation. For the situation when outpatient asthma management has failed, an approach to the critically ill pregnant patient with status asthmaticus is detailed. Multidisciplinary teams that include pulmonary specialists, obstetricians, primary care providers, nurses, pharmacists, and asthma educators improve the care of pregnant women with asthma.

Indexed as

Adrenal Cortex HormonesAnti-Asthmatic AgentsAsthmaBronchodilator AgentsFemaleHumansPatient Education as TopicPregnancyPregnancy ComplicationsRespiration, ArtificialRespiratory Function TestsAdrenal Cortex HormonesAnti-Asthmatic AgentsBronchodilator Agentsasthmacritical carepregnancyprimary medicine

Identifiers

PMID28867295
PMCPMC5815874
OpenAlexW2751440696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.