Evidence map›Paper›PMID 28867065›Full record

ArticleThe Journal of pediatrics2017

Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International Clinical Registry and Genetic Repository.

Joy Wan, Jack Steiner, Eulalia Baselga, Francine Blei, Maria Cordisco, Maria C Garzon, Deborah S Goddard, Anita Haggstrom, Alfons Krol, Ilona J Frieden and 6 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Ophthalmic screening in phakomatoses.Frontiers in cell and developmental biology · 2026
    Article
  2. PHACE syndrome: looking backward and forward.Orphanet journal of rare diseases · 2025
    Review
  3. Review
  4. Article
  5. Infantile hemangiomas: a dermatologist's perspective.European journal of pediatrics · 2024
    Review
  6. Review
  7. Review
  8. [Infantile haemangioma: an update].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 13 institutions in 4 countries.

Joy WanDepartment of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA. Electronic address: Joy.Wan@uphs.upenn.edu.
Jack SteinerDepartment of Dermatology, Medical College of Wisconsin, Milwaukee, WI.
Eulalia BaselgaPediatric Dermatology Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Francine BleiVascular Anomalies Program, Lenox Hill Hospital, Northwell Health, New York, NY.
Maria CordiscoDepartment of Dermatology, University of Rochester Medical Center, Rochester, NY.
Maria C GarzonDepartment of Dermatology, Columbia University, New York, NY; Department of Pediatrics, Columbia University, New York, NY.
Deborah S GoddardKuchnir Dermatology & Dermatologic Surgery, Framingham and Milford, MA.
Anita HaggstromDepartment of Dermatology, School of Medicine, Indiana University, Indianapolis, IN.
Alfons KrolDepartment of Dermatology, Oregon Health & Science University, Portland, OR; Department of Pediatrics, Oregon Health & Science University, Portland, OR.
Ilona J FriedenDepartment of Dermatology, University of California San Francisco, San Francisco, CA.
Denise MetryDepartment of Dermatology, Texas Children's/Baylor College of Medicine, Houston, TX.
Kimberly D MorelDepartment of Dermatology, Columbia University, New York, NY; Department of Pediatrics, Columbia University, New York, NY.
Judith M A VerhagenDepartment of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Orli WargonDepartment of Pediatric Dermatology, Sydney Children's Hospital School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.
Beth A DroletDepartments of Dermatology and Pediatrics, Section of Pediatric Dermatology, Medical College of Wisconsin, Milwaukee, WI.
Dawn H SiegelDepartments of Dermatology and Pediatrics, Section of Pediatric Dermatology, Medical College of Wisconsin, Milwaukee, WI.
Medical College of Wisconsin · USColumbia University · USBaylor College of Medicine · USErasmus MC · NLHospital de Sant Pau · ESIndiana University – Purdue University Indianapolis · USKuchnir Dermatology & Dermatologic Surgery · USLenox Hill Hospital · USOregon Health & Science University · USUniversity of California, San Francisco · USUniversity of Pennsylvania · USUniversity of Rochester Medical Center · USUNSW Sydney · AU

Funding

Penn Dermatology Research Training ProgramT32AR007465 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice, David Joel Margolis · 1986 to 2026
$9.0M
Pathogenesis and Natural History in a Longitudinal Hemangioma Syndrome CohortR01AR064258 · NIAMS · MEDICAL COLLEGE OF WISCONSIN · PI SIEGEL, DAWN H. · 2014 to 2016
$1.4M
NIAMS NIH HHS R01 AR064258NIAMS NIH HHS T32 AR007465
6 · The paper itself

Abstract

The cause of PHACE syndrome is unknown. In a study of 218 patients, we examined potential prenatal risk factors for PHACE syndrome. Rates of pre-eclampsia and placenta previa in affected individuals were significantly greater than in the general population. No significant risk factor differences were detected between male and female subjects.

Indexed as

Aortic CoarctationCross-Sectional StudiesEye AbnormalitiesFemaleHumansInfant, NewbornMaleNeurocutaneous SyndromesPlacenta PreviaPre-EclampsiaPregnancyPrenatal CareRegistriesRisk FactorsUnited Statesdisease pathogenesishemangiomaperinatal risk factors

Identifiers

PMID28867065
PMCPMC5690843
OpenAlexW2751449867

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.