ArticleEndocrine2017
The radiographically diagnosed adrenal myelolipoma: what do we really know?
Article in Endocrine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Laparoscopic adrenalectomy via transperitoneal and retroperitoneal approaches for bilateral giant adrenal myelolipoma: A case report and literature review.Experimental and therapeutic medicine · 2025Article
- Large sized bilateral adrenal myelolipoma with spontaneous retroperitoneal hemorrhage: a case series.Annals of medicine and surgery (2012) · 2025Article
- Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma.IJU case reports · 2025Article
- Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study.Medicina (Kaunas, Lithuania) · 2024Article
- Management of patients with adrenal myelolipoma: experience from a tertiary referral centre.Irish journal of medical science · 2024Observational
- Laparoscopic resection of giant adrenal myelolipoma: A case report with review of literature.Radiology case reports · 2024Article
- Concurrent adrenal and extra-adrenal myelolipoma: A case report.International journal of surgery case reports · 2024Article
- Review
- Coexistence of Bilateral Giant Adrenal Myelolipomas and Congenital Adrenal Hyperplasia: A Case Report.Cureus · 2023Article
- A case of adrenal myelolipoma complicated with Prader-Willi syndrome.IJU case reports · 2023Article
- A large adrenal myelolipoma: case report and review of the literature.Journal of surgical case reports · 2023Article
- Two Cases of Adrenal Malignancy With Macroscopic Fat.JCEM case reports · 2023Article
- [Adrenal myelolipoma, review of the literature in Mexico apropos of two cases].Revista medica del Instituto Mexicano del Seguro Social · 2022Review
- Giant symptomatic adrenal myelolipoma: A case report.Annals of medicine and surgery (2012) · 2022Article
- Adrenal myelolipomas.The lancet. Diabetes & endocrinology · 2021Review
- A Rare Case of Hemorrhagic Giant Adrenal Myelolipoma: Radiographic and Pathologic Correlation.Cureus · 2021Article
- Clinical course of adrenal myelolipoma: A long-term longitudinal follow-up study.Clinical endocrinology · 2020Article
- Functional Adrenal Collision Tumor in a Patient with Cushing's Syndrome.Case reports in endocrinology · 2020Article
- Development of multiple adrenal myelolipomas after trauma-induced adrenal haemorrhage.BMJ case reports · 2019Article
- Surgery for adrenal angiomyelolipoma: an individualized concept.Langenbeck's archives of surgery · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAdrenal myelolipomas are uncommon, benign tumors of the adrenal glands that are not routinely evaluated for autonomous hormone secretion or followed by repeat imaging, but may lead to retroperitoneal hemorrhage. Little is known about the natural history these tumors with the majority of previous publications being confined to case reports and small case series.
methodsWe reviewed the computed tomography (CT) reports of 62,279 patients evaluated at a tertiary referral center between 2002 and 2015 for the presence of an adrenal myelolipoma >1 cm in size. We then reviewed the CT imaging and patient charts to determine tumor size, growth, evidence of retroperitoneal hemorrhage, and endocrine dysfunction.
resultsWe identified 150 (0.24%) patients with 155 radiographically diagnosed adrenal myelolipomas found on a CT scan during our study period. The median tumor size at discovery was 2.1 cm. Twelve (7.7%) tumors were >6 cm. Sixty-nine (46%) patients had a follow-up CT with a mean time interval between scans of 3.9 years. Eleven tumors (16%) grew over our follow-up period with a median growth rate of 0.16 cm/year. No patient developed a retroperitoneal hemorrhage. Twenty (13%) patients underwent an evaluation for endocrine dysfunction. Three patients had evidence of hypercortisolism and one patient had primary aldosteronism.
conclusionThe majority of radiographically diagnosed adrenal myelolipomas found on abdominal CT imaging are small and slow growing. Retroperitoneal hemorrhage is uncommon, but the rate of associated endocrine dysfunction may be underestimated.
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