Evidence map›Paper›PMID 28866658›Full record

ArticleJournal of biomedical research2017

Proteomic analysis of the dorsal spinal cord in the mouse model of spared nerve injury-induced neuropathic pain.

Eun-Sung Park, Jung-Mo Ahn, Sang-Min Jeon, Hee-Jung Cho, Ki-Myung Chung, Je-Yoel Cho, Dong-Ho Youn

Open access · hybridAbstract read
In one paragraph

Article in Journal of biomedical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Eun-Sung ParkDepartment of Oral Physiology, School of Dentistry, Kyungpook National University, Jung-gu, Daegu 41940, R. O. Korea.
Jung-Mo AhnBiocenter, Incheon Technopark, Yeonsu-gu, Incheon 406-840, R. O. Korea.
Sang-Min JeonDepartment of Anatomy, School of Medicine, Kyungpook National University, Dong-in Dong, Daegu 700-422, R. O. Korea.
Hee-Jung ChoDepartment of Anatomy, School of Medicine, Kyungpook National University, Dong-in Dong, Daegu 700-422, R. O. Korea.
Ki-Myung ChungDepartment of Physiology and Neuroscience, College of Dentistry and Research Institute of Oral Science, Gangneung-Wonju National University, Gangneung,Gangwon-do 210-702, R. O. Korea.
Je-Yoel ChoDepartment of Biochemistry, College of Veterinary Medicine, Seoul National University, Seoul 151-742, R. O. Korea.
Dong-Ho YounDepartment of Oral Physiology, School of Dentistry, Kyungpook National University, Jung-gu, Daegu 41940, R. O. Korea.
Kyungpook National University · KRDaejeon Technopark · KRGangneung–Wonju National University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral nerve injury often causes neuropathic pain and is associated with changes in the expression of numerous proteins in the dorsal horn of the spinal cord. To date, proteomic analysis method has been used to simultaneously analyze hundreds or thousands of proteins differentially expressed in the dorsal horn of the spinal cord in rats or dorsal root ganglion of rats with certain type of peripheral nerve injury. However, a proteomic study using a mouse model of neuropathic pain could be attempted because of abundant protein database and the availability of transgenic mice. In this study, whole proteins were extracted from the ipsilateral dorsal half of the 4

Identifiers

PMID28866658
PMCPMC6307668
OpenAlexW2903406914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.