ArticleIEEE transactions on visualization and computer graphics2018
A Virtual Reality Visualization Tool for Neuron Tracing.
Article in IEEE transactions on visualization and computer graphics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- VRoot: A VR-Based application for manual root system architecture reconstruction.Plant phenomics (Washington, D.C.) · 2025Article
- A FAIR, open-source virtual reality platform for dendritic spine analysis.Patterns (New York, N.Y.) · 2024Article
- u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions.Cell reports methods · 2023Article
- NeuRegenerate: A Framework for Visualizing Neurodegeneration.IEEE transactions on visualization and computer graphics · 2023Article
- A Comprehensive, FAIR File Format for Neuroanatomical Structure Modeling.Neuroinformatics · 2022Article
- A Novel Gesture-Based Control System for Fluorescence Volumetric Data in Virtual Reality.Sensors (Basel, Switzerland) · 2021Article
- Virtual reality for 3D histology: multi-scale visualization of organs with interactive feature exploration.BMC cancer · 2021Article
- Virtual and augmented reality for biomedical applications.Cell reports. Medicine · 2021Review
- Improving the Usability of Virtual Reality Neuron Tracing with Topological Elements.IEEE transactions on visualization and computer graphics · 2021Article
- New Approach to Accelerated Image Annotation by Leveraging Virtual Reality and Cloud Computing.Frontiers in bioinformatics · 2021Article
- BigTop: a three-dimensional virtual reality tool for GWAS visualization.BMC bioinformatics · 2020Article
- TeraVR empowers precise reconstruction of complete 3-D neuronal morphology in the whole brain.Nature communications · 2019Article
- Challenges of Processing and Analyzing Big Data in Mesoscopic Whole-brain Imaging.Genomics, proteomics & bioinformatics · 2019Article
- Experimental and Computational Methods for the Study of Cerebral Organoids: A Review.Frontiers in neuroscience · 2019Review
- Visualization of Neuronal Structures in Wide-Field Microscopy Brain Images.IEEE transactions on visualization and computer graphics · 2018Article
- Integrating light-sheet imaging with virtual reality to recapitulate developmental cardiac mechanics.JCI insight · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Tracing neurons in large-scale microscopy data is crucial to establishing a wiring diagram of the brain, which is needed to understand how neural circuits in the brain process information and generate behavior. Automatic techniques often fail for large and complex datasets, and connectomics researchers may spend weeks or months manually tracing neurons using 2D image stacks. We present a design study of a new virtual reality (VR) system, developed in collaboration with trained neuroanatomists, to trace neurons in microscope scans of the visual cortex of primates. We hypothesize that using consumer-grade VR technology to interact with neurons directly in 3D will help neuroscientists better resolve complex cases and enable them to trace neurons faster and with less physical and mental strain. We discuss both the design process and technical challenges in developing an interactive system to navigate and manipulate terabyte-sized image volumes in VR. Using a number of different datasets, we demonstrate that, compared to widely used commercial software, consumer-grade VR presents a promising alternative for scientists.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.