ArticleMagnetic resonance imaging2017
Static and dynamic liver stiffness: An ex vivo porcine liver study using MR elastography.
Article in Magnetic resonance imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Magnetic Resonance Elastography for Staging Liver Fibrosis in the Oncopig.Diagnostics (Basel, Switzerland) · 2024Article
- Gunshot wounds in parenchymatous organs: the morphology mainly depends on the physical properties of the affected tissues.International journal of legal medicine · 2023Article
- Portal hypertension is the main driver of liver stiffness in advanced liver cirrhosis.Physiological research · 2021Article
- Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Magnetic resonance elastography (MRE) is an MRI-based noninvasive technique for quantitatively assessing tissue stiffness. The hypothesis of this study is that stiffness increases with portal pressure. We further hypothesized that the rate of stiffness change with pressure would be larger in liver tissue treated to simulate the stiffening effects of fibrosis. In agreement with our hypothesis, the formalin-treated livers were stiffer than the untreated livers, and in both groups the liver stiffness increased with portal venous pressure. The rate of stiffness change with portal pressure was significantly greater after formalin treatment. In this study, we have developed an ex vivo liver model incorporating portal venous pressure variations and observed significant changes in liver stiffness due to portal pressure. This model could be useful for understanding and investigating the changes in the static and dynamic components of liver stiffness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.